Protein Alignment Cyp313a3 and CYP4V2

DIOPT Version :9

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_997235.3
• Gene: CYP4V2 / 285440
• HGNCID: 23198
• Length: 525
• Species: Homo sapiens
• Alignment Length: 486
• Identity: 136/486 - (27%)
• Similarity: 227/486 - (46%)
• Gaps: 68/486 - (13%)

  Fly    39 PILGIA----------FEYLITYKRKMSIRTKYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLS 93
            |::|.|          |:.:|.|..:.    ::|.:    ..:||||.|.|...:.:..|.|..|
Human    58 PLVGHALLMKPDGREFFQQIIEYTEEY----RHMPL----LKLWVGPVPMVALYNAENVEVILTS 114

  Fly    94 PECLNRSSIFSKPVNSCTGDGLLSLEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLD 158
            .:.:::||:: |.:....|.|||:...:||..|||.|.|.|...:|..||.|.|.:|..||..|:
Human   115 SKQIDKSSMY-KFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDFLDIMNEQANILVKKLE 178

  Fly   159 SLVGQGEKKVRDDIVRWSFRIATQTTVGTDVKKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNK 223
            ..:.|........|...:..|..:|.:|.::...::..::.|...|. ..::|...:.:|:....
Human   179 KHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYR-MSEMIFRRIKMPWLWLD 242

  Fly   224 IFSTL--GGFETQKALAKSNVNKMIGTIVDKKLMTKPES------------GSQPE--------- 265
            ::..:  .|:|.:|:|      :::.|..:..:..:...            ||.|.
Human   243 LWYLMFKEGWEHKKSL------QILHTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLD 301

  Fly   266 -ITSVINKAIELHRNGEMSREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKE 329
             :.||.:     .....:|.|:::.|..:|:....:||...:..:|.||...||.|..|..||.:
Human   302 LLLSVTD-----DEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDD 361

  Fly   330 LFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIF 394
            :|. ..|...|.:||:::.:||.|:.|||||.||||...|....|..: :|..:.||....|..:
Human   362 VFG-KSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEV-AGYRVLKGTEAVIIPY 424

  Fly   395 ATHRNRDHWGTDPSSFNPDHFLPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNC 459
            |.||:..:: .:|..|.|:.|.|:|.:.||||||:|||.|.|||||.|:.:|..|..||.|||:.
Human   425 ALHRDPRYF-PNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHF 488

  Fly   460 KVSTSFRYEDLEFVDNIGME----LAQSPGL 486
            .:.::.:.|:|      |:|    |..|.|:
Human   489 WIESNQKREEL------GLEGQLILRPSNGI 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	129/457 (28%)
CYP4V2	NP_997235.3	p450	55..517	CDD:278495	136/486 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810