Protein Alignment Cyp313a3 and Cyp4a8

DIOPT Version :10

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_113793.2
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 491
• Identity: 115/491 - (23%)
• Similarity: 199/491 - (40%)
• Gaps: 80/491 - (16%)

  Fly     3 TFQLLLAVGVCFWIYFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLITYKRKMSIRTKYMDI--- 64
            |..|||.....|:::..|..|...    :.|.|......|          .|:....::.||
  Rat    26 TVLLLLFKTAQFYLHRRWLLRATQ----QFPSPPSHWFFG----------HKIPKDQEFQDILTR 76

  Fly    65 ---YGSTCLVWV-GPTPFVITRDPKIAEEI-------------FLSPECLNRSSIFSKPVNSCTG 112
               :.|.|..|: |....:...||...:.|             ||:|               ..|
  Rat    77 VKNFPSACPQWLWGSNVRIQVYDPDYMKLILGRSDPKSHHSYRFLAP---------------WIG 126

  Fly   113 DGLLSLEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEKKVRDDIVRWSF 177
            .|||.|....|...|:.|.|||..:.|..::.|.....:.::...:.:|||       |.....|
  Rat   127 YGLLLLNGQTWFQHRRMLTPAFHYDTLKPYVGIMADSVRIMLDKWEQIVGQ-------DSTLEIF 184

  Fly   178 RIATQTTVGTDVK----KDASFKNDSVLKSY----ETFMKIIVMNVLLPFTHNKIFSTL--GGFE 232
            :..|..|:.|.:|    ::.|.:.|...|||    |....:....:...|..|.|..:|  .|.:
  Rat   185 QHITLMTLDTIMKCAFSQEGSVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSNGRK 249

  Fly   233 TQKA--LAKSNVNKMI----GTIVDKKLMTKPESGSQPEITSVINKAIELHRNGEMSREEVQSEC 291
            .:.|  ||..:.:::|    ..:.|::.:.|.:...:.:...::..| .:.....:|.:::::|.
  Rat   250 ARSAWQLAHEHTDQVIKSRKAQLQDEEELQKVKQKRRLDFLDILLFA-RIENGSSLSDKDLRAEV 313

  Fly   292 CSFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGD-FEVTYDDLQRMVFLERVVN 355
            .:|:....:||...:......||..||||....:|::.|.   || ..:|:|||.:|.:....:.
  Rat   314 DTFMFEGHDTTASGISWIFYALATNPEHQQGCRKEIQSLL---GDGASITWDDLDKMPYTTMCIK 375

  Fly   356 ETLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNV 420
            |.||:.|.|....|..........|..:|||:.:.:..:..|.|...| .:|..|:|..|.|::
  Rat   376 EALRIYPPVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLHHNPTVW-PNPEVFDPYRFAPES- 438

  Fly   421 RDRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKIL 456
             .||.::::|||.|.|||||.::.:...|:|::..|
  Rat   439 -SRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTL 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	CYP313-like	66..487	CDD:410680	102/422 (24%)
Cyp4a8	NP_113793.2	CYP4B-like	70..503	CDD:410771	104/433 (24%)