Protein Alignment Cyp313a3 and CYP4Z1

DIOPT Version :9

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_835235.1
• Gene: CYP4Z1 / 199974
• HGNCID: 20583
• Length: 505
• Species: Homo sapiens
• Alignment Length: 496
• Identity: 127/496 - (25%)
• Similarity: 210/496 - (42%)
• Gaps: 74/496 - (14%)

  Fly     7 LLAVGVC-----FWIYFLWSRRR--LYMMHFKIPGPMGLPILGIAFEYLITYKRKMSIRTKYMDI 64
            ||.:.:|     |.:..|:.|||  :..:|. .|.|......|....|.:   ::..:..|.|:.
Human    15 LLLILLCMSLLLFQVIRLYQRRRWMIRALHL-FPAPPAHWFYGHKEFYPV---KEFEVYHKLMEK 75

  Fly    65 YGSTCLVWVGP-TPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLSLEASKWVDRRK 128
            |.....:|||| |.|....||..|:.:....:  .:|::..|.:.|..|.||::|:.|||...|:
Human    76 YPCAVPLWVGPFTMFFSVHDPDYAKILLKRQD--PKSAVSHKILESWVGRGLVTLDGSKWKKHRQ 138

  Fly   129 NLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEK---------KVRDDIVRWSFRIATQTT 184
            .:.|.|..::|..|:.:.:...:.::...:..:.|..:         ...|.|::.:|
Human   139 IVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQHVSLMTLDSIMKCAF------- 196

  Fly   185 VGTDVKKDASFKNDSVLKSYETFMKIIV---------MNVLLPFTHNKI---FSTLGGFETQKAL 237
                 ....|.:.||.|.||   :|.:.         ||..|  .||.:   ||:.|..
Human   197 -----SHQGSIQLDSTLDSY---LKAVFNLSKISNQRMNNFL--HHNDLVFKFSSQGQI------ 245

  Fly   238 AKSNVNKMIGTIVDKKLMTKPESGSQPEITSVINK----------AIELHRNGEMSREEVQSECC 292
             .|..|:.:....:|.:..:.||...........|          :.:.....:.|..::|:|..
Human   246 -FSKFNQELHQFTEKVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVK 309

  Fly   293 SFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGD-FEVTYDDLQRMVFLERVVNE 356
            :|:.|..:||...:...|..||.:||||.....|::||.   || ..:|::.|.:|.:....:.|
Human   310 TFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELL---GDGSSITWEHLSQMPYTTMCIKE 371

  Fly   357 TLRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVR 421
            .|||...|....|...:......|..:|.|:.:.|:|:|.|.|...| .||..|||..|..:|..
Human   372 CLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFW-EDPQVFNPLRFSRENSE 435

  Fly   422 DRHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCKVS 462
            ..||||:||||.|.|||||..:.::..|:|::..|...|::
Human   436 KIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLA 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	118/463 (25%)
CYP4Z1	NP_835235.1	p450	47..500	CDD:278495	118/463 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920