Protein Alignment Cyp313a3 and CYP26A1

DIOPT Version :9

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_000774.2
• Gene: CYP26A1 / 1592
• HGNCID: 2603
• Length: 497
• Species: Homo sapiens
• Alignment Length: 466
• Identity: 112/466 - (24%)
• Similarity: 202/466 - (43%)
• Gaps: 33/466 - (7%)

  Fly     6 LLLAVGVCFW-IYFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLITYKRKMSI-RTKYMDIYGST 68
            ||....:..| :|.:..|.|...:... ||.||.|..|...:.::..::.:.: |.||..||.:.
Human    19 LLFLAAIKLWDLYCVSGRDRSCALPLP-PGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTH 82

  Fly    69 CLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLS-LEASKWVDRRKNLNP 132
              ::..||..|:..|.  ...|.|....| .|..:...|.:..|.|.|| |..|....|:|.:..
Human    83 --LFGRPTVRVMGADN--VRRILLGEHRL-VSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMR 142

  Fly   133 AFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEK--KVRDDIVRWSFRIATQTTVGTD--VKKDA 193
            ||.:..|..::|:...|   :.:.|:..:..||:  .|..::.|..||||.:..:|.:  :..|.
Human   143 AFSREALECYVPVITEE---VGSSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDG 204

  Fly   194 SFKNDSVLKSYETFMKIIVMNVLLPFTHNKIFSTLGGFETQKA--LAKSNVNKMIGTIVDKKLMT 256
            ..:...|....|....:..:.:.:||:        |.:...||  |..:.:.:.|...:.....:
Human   205 DSEQQLVEAFEEMTRNLFSLPIDVPFS--------GLYRGMKARNLIHARIEQNIRAKICGLRAS 261

  Fly   257 KPESGSQPEITSVINKAIELHRNGEMSREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQD 321
            :...|.:..:..:|..:.|  |...:..:.::......:....|||.......:..|.::|....
Human   262 EAGQGCKDALQLLIEHSWE--RGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQ 324

  Fly   322 TVYQELKE---LFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRLSSGVVI 383
            .|.:|||.   |.....|.::..:.|:::.::..|:.|||||.|.||...|..::.|.| :|..|
Human   325 KVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQI 388

  Fly   384 PKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSS 448
            |||..:...|..||...:.: |:...||||.|:..:..|...:::|||..|.|:|:|.::..:..
Human   389 PKGWNVIYSICDTHDVAEIF-TNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILL 452

  Fly   449 KLALSKILRNC 459
            |:...::.|:|
Human   453 KIFTVELARHC 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	106/438 (24%)
CYP26A1	NP_000774.2	p450	14..492	CDD:299894	112/466 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4598
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950