Protein Alignment Cyp313a3 and Cyp46a1

DIOPT Version :9

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_034140.1
• Gene: Cyp46a1 / 13116
• MGIID: 1341877
• Length: 500
• Species: Mus musculus
• Alignment Length: 482
• Identity: 119/482 - (24%)
• Similarity: 217/482 - (45%)
• Gaps: 67/482 - (13%)

  Fly     6 LLLAVGVCFWIYFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLITYKRK-----MSIRTKYMD-- 63
            :|||.|:|  ..|:...|..|.   .||||   |.......:|..:.:|     ..::..::|
Mouse    12 VLLAFGLC--CTFVHRARSRYE---HIPGP---PRPSFLLGHLPYFWKKDEDCGRVLQDVFLDWA 68

  Fly    64 -IYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGD-----GLLS-LEAS 121
             .||....|.|.....||...|:..::..:|.: .|:.|...:.:.:..|:     ||:| .:..
Mouse    69 KKYGPVVRVNVFYKTSVIVTSPESVKKFLMSTK-YNKDSKMYRALQTVFGERLFGQGLVSECDYG 132

  Fly   122 KWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLV-GQGEKKVRDDIVRWSFRIATQTTV 185
            :|..:||.::.||.::.|:|.:..||.:|:.||..|::.. ||....::|        :.|..|:
Mouse   133 RWYKQRKVMDLAFSRSSLVSLMETFNEKAEQLVEILEAKADGQTPVSMQD--------MLTCATI 189

  Fly   186 GTDVKKDASFKNDSVL-----KSYETFMKIIVMNVLLPFTHNKIFSTLGGFETQKALAKSNVN-- 243
              |:...|:|..::.:     |.....:|:::..:  ..:.|.:...:.|...|....:.::.
Mouse   190 --DILAKAAFGMETSMLLGAQKPLSQAVKVMLEGI--SASRNTLAKFMPGKRKQLREIRESIRLL 250

  Fly   244 KMIGT--IVDKKLMTKPESGSQPEITSVINKAIELHRNGEMSREEVQSECCSFVVAAFETTGDTV 306
            :.:|.  :..::...|.......:|.:.|.||.|    |....|.:.....:|.:|..||:.:.:
Mouse   251 RQVGKDWVQRRREALKRGEDMPADILTQILKAEE----GAQDDEVLLDNFVTFFIAGHETSANHL 311

  Fly   307 YHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPR-- 369
            ...::.|:..||....:..|:.|:  |.....:.|:||.|:.:|.:|:.|:|||.|....|.|
Mouse   312 AFTVMELSRQPEIVARLQAEVDEV--VGSKRHLDYEDLGRLQYLSQVLKESLRLYPPAWGTFRLL 374

  Fly   370 --ETIRDFRLSSGVVIPKGVGIGIDIFATH--RNRDHWGTDPSSFNPDHFLPDNVRDRHPYAYIP 430
              ||:.|     ||.:|....:   :|:|:  ...|.:..||.:||||.|.|...:.|  :.|.|
Mouse   375 EEETLID-----GVRVPGNTPL---LFSTYVMGRMDTYFEDPLTFNPDRFGPGAPKPR--FTYFP 429

  Fly   431 FSKGRRNCIGWKYGLMSSKLALSKILR 457
            ||.|.|:|||.::..|..|:.::|:|:
Mouse   430 FSLGHRSCIGQQFAQMEVKVVMAKLLQ 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	110/455 (24%)
Cyp46a1	NP_034140.1	p450	34..466	CDD:278495	110/455 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010