Protein Alignment Cyp313a3 and Cyp3a13

DIOPT Version :10

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 498
• Identity: 142/498 - (28%)
• Similarity: 219/498 - (43%)
• Gaps: 75/498 - (15%)

  Fly     1 MDTFQLLLAVGVCFWIYFLWSRRRLYMMH--FK---IPGPMGLPILGIAFEYLITYKR-----KM 55
            |:|:.||....|..::|...|       |  ||   ||||..||.||.    ::.|::     .:
Mouse     9 METWMLLATSLVLLYLYGTHS-------HGIFKKLGIPGPKPLPFLGT----ILAYQKGFWECDI 62

  Fly    56 SIRTKYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSK-----PVNSCTGDGL 115
            ....||..::|    ::.|..|.:...||.|.:.: |..||.   |.|:.     ||      |:
Mouse    63 QCHKKYGKMWG----LYDGRQPVLAITDPDIIKTV-LVKECY---STFTNRRRFGPV------GI 113

  Fly   116 LS-----LEASKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEKKVRDDIV-R 174
            |.     .|..:|...|..|:|.|....|....||.|.....||..:...:|:|:.....||. .
Mouse   114 LKKAISISENEEWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGA 178

  Fly   175 WSFRIATQTTVGTDV-----KKDASFKNDSVLKSYETFMKIIVMNVLLPFTHNKIFSTLGGFETQ 234
            :|..:.|.|:.|.::     .:|...:....|..::.|..:.:...|.||. ..:|..|     .
Mouse   179 YSMDVITATSFGVNIDSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFL-TPVFDAL-----N 237

  Fly   235 KALAKSNVNKMIGTIVDK---KLMTKPESGSQPEITSVIN----KAIELHRNGEMSREEVQSECC 292
            .:|...:|.....|.|::   ..|.:.|......:..:||    |..|.|:  .:|..|:.::..
Mouse   238 VSLFPRDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTKESHK--ALSDVEIVAQSV 300

  Fly   293 SFVVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNET 357
            .|:.|.:|||...:..||.|||:.|:.|..:..|:....|  .....|||.|.:|.:|:.|||||
Mouse   301 IFIFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAALP--NKAPATYDTLLQMEYLDMVVNET 363

  Fly   358 LRLIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRD 422
            |||.|......|....|..: :|:.||||..:.|..||.|::..:| .:|..|.|:.|...|...
Mouse   364 LRLYPIAGRLERVCKTDVEI-NGLFIPKGTVVMIPTFALHKDPKYW-PEPEEFRPERFSKKNQDS 426

  Fly   423 RHPYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRN-----CK 460
            .:||.|:||..|.|||||.::.|::.|:||.::|:|     ||
Mouse   427 INPYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCK 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	CYP313-like	66..487	CDD:410680	121/423 (29%)
Cyp3a13	NP_031845.1	CYP3A	67..492	CDD:410743	123/429 (29%)