Protein Alignment Cyp313a3 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Alignment Length: 466
• Identity: 113/466 - (24%)
• Similarity: 209/466 - (44%)
• Gaps: 33/466 - (7%)

  Fly     6 LLLAVGVCFW-IYFLWSRRRLYMMHFKIPGPMGLPILGIAFEYLITYKRKMSI-RTKYMDIYGST 68
            ||....:..| :|.:.||.|...:... ||.||.|..|...:.::..::.:.: |.||..||.:.
Mouse    19 LLFLAALKLWDLYCVSSRDRSCALPLP-PGTMGFPFFGETLQMVLQRRKFLQMKRRKYGFIYKTH 82

  Fly    69 CLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLS-LEASKWVDRRKNLNP 132
              ::..||..|:..|.  ...|.|....| .|..:...|.:..|.|.|| |..|....|:|.:..
Mouse    83 --LFGRPTVRVMGADN--VRRILLGEHRL-VSVHWPASVRTILGAGCLSNLHDSSHKQRKKVIMQ 142

  Fly   133 AFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEK--KVRDDIVRWSFRIATQTTVGTDVKKDASF 195
            ||.:..|..::|:...|..:.   |:..:..||:  .|..::.|..||||.:..:|.:.......
Mouse   143 AFSREALQCYVPVIAEEVSSC---LEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPGPAGGG 204

  Fly   196 KND-SVLKSYETFMK-IIVMNVLLPFTHNKIFSTLGGFETQKA--LAKSNVNKMIGTIVDKKLMT 256
            ::: .:::::|...: :..:.:.:||:        |.:...||  |..:.:.:.|...:.:...|
Mouse   205 EDEQQLVEAFEEMTRNLFSLPIDVPFS--------GLYRGVKARNLIHARIEENIRAKIRRLQAT 261

  Fly   257 KPESGSQPEITSVINKAIELHRNGEMSREEVQSECCSFVVAAFETTGDTVYHALILLAMFPEHQD 321
            :|:.|.:..:..:|..:.|  |...:..:.::......:....|||.......:..|.::|....
Mouse   262 EPDGGCKDALQLLIEHSWE--RGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQ 324

  Fly   322 TVYQELKE---LFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFRLSSGVVI 383
            .|.:|:|.   |.....|.::..:.|:::.:...|:.|||||.|.||...|..::.|.| :|..|
Mouse   325 KVREEIKSKGLLCKSNQDNKLDMETLEQLKYTGCVIKETLRLNPPVPGGFRVALKTFEL-NGYQI 388

  Fly   384 PKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRHPYAYIPFSKGRRNCIGWKYGLMSS 448
            |||..:...|..||...|.: |:...||||.|:..:..|...:::|||..|.|:|:|.::..:..
Mouse   389 PKGWNVIYSICDTHDVADIF-TNKEEFNPDRFIVPHPEDASRFSFIPFGGGLRSCVGKEFAKILL 452

  Fly   449 KLALSKILRNC 459
            |:...::.|:|
Mouse   453 KIFTVELARHC 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	CYP313-like	66..487	CDD:410680	95/404 (24%)
Cyp26a1	NP_031837.2	CYP26A1	55..490	CDD:410731	101/429 (24%)