Protein Alignment Cyp313a3 and Cyp3a59

DIOPT Version :10

• Sequence 1: NP_650170.2
• Gene: Cyp313a3 / 41488
• FlyBaseID: FBgn0038007
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001098630.1
• Gene: Cyp3a59 / 100041449
• MGIID: 3769707
• Length: 503
• Species: Mus musculus
• Alignment Length: 492
• Identity: 137/492 - (27%)
• Similarity: 223/492 - (45%)
• Gaps: 66/492 - (13%)

  Fly     1 MDTFQLLLAVGVCFWIYFLWSRRRLYMMH--FK---IPGPMGLPILGIAFEYLI-TYKRKMSIRT 59
            ::|:.||:...|.|:||..:|       |  ||   ||||..||:.|..|.|.. .:|.......
Mouse     9 IETWVLLVTSLVFFYIYGTYS-------HGLFKKLGIPGPKPLPLFGTIFNYFDGMWKFDEDCYK 66

  Fly    60 KYMDIYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIF-SKPVNSCTG---DGLLSLEA 120
            ||..|:|    .:|||.|.:...||:|. :|.|..||.   |:| ::|.....|   ..:...|.
Mouse    67 KYGKIWG----FYVGPKPILAIMDPEII-KIVLVKECY---SVFTNRPTLGPVGFLKKSITISED 123

  Fly   121 SKWVDRRKNLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEK-KVRDDIVRWSFRIATQTT 184
            .:|...|..|:|.|....|....||.......||..|.....:||. .::|....:|..:.|.|:
Mouse   124 EEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINMKDIFGAYSMDVITGTS 188

  Fly   185 VGTDVKKDASFKNDSVLKS-----YETFMKIIVMNVLLPFTHNKIFSTLGGFETQKALAKSNVN- 243
            .|.::....:.:|..|.|:     ::.|...::..:|.||. ..|:..|    ......:.::|
Mouse   189 FGVNIDSLNNPQNPFVQKTKKILKFKIFDPFLLSTILFPFL-TPIYEML----NLSIFPRDSMNF 248

  Fly   244 --KMIGTIVDKKLMTKPESGSQPEITSVINKA--IELHRN-----GEMSRE-----EVQSECCSF 294
              |.:..:..::|.:|.:           |:.  ::|..|     |:.|::     |:.::...|
Mouse   249 FKKFVKRMKKERLASKQK-----------NRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVIF 302

  Fly   295 VVAAFETTGDTVYHALILLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLR 359
            :...::.|..::...:..||..|:.|..:..|:....|  ....||||.|..|.:|:.||||:||
Mouse   303 IFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLP--NKAPVTYDALMDMEYLDMVVNESLR 365

  Fly   360 LIPSVPFTPRETIRDFRLSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRH 424
            |.|:.....|.:.:|..: :||.||||..:.|.|:..|||.::| .:|..|.|..|..:|..:..
Mouse   366 LYPTAIRLERVSKKDVEI-NGVFIPKGTVVMIPIYPLHRNPEYW-PEPQEFCPGRFSKENEGNID 428

  Fly   425 PYAYIPFSKGRRNCIGWKYGLMSSKLALSKILRNCKV 461
            ||.|:||..|.|||:..::.|:|.|||:..:|:|..|
Mouse   429 PYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTV 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a3	NP_650170.2	CYP313-like	66..487	CDD:410680	113/421 (27%)
Cyp3a59	NP_001098630.1	CYP3A	67..492	CDD:410743	116/427 (27%)