DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a2 and CYP735A2

DIOPT Version :9

Sequence 1:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_176882.1	Gene:	CYP735A2 / 843031	AraportID:	AT1G67110	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	124/531 - (23%)
Similarity:	230/531 - (43%)	Gaps:	80/531 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLIAASLILWI-------RFLWSRR-KLYMLMMQLPGRMGLPLLGN-----------------SV 45
            |:|..:|||.:       .||..|| |.:|....:.|.....|.||                 |:
plant    11 LVIVMTLILRVLYDSICCYFLTPRRIKKFMERQGITGPKPRLLTGNIIDISKMLSHSASNDCSSI 75

  Fly    46 RYLIISRGRMSSRTTYMDKHGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSS----QTTNA 106
            .:.|:.| .:....::..::|..::.|.||.|.:...:.::.:::||....:...|    |.|..
plant    76 HHNIVPR-LLPHYVSWSKQYGKRFIMWNGTEPRLCLTETEMIKELLTKHNPVTGKSWLQQQGTKG 139

  Fly   107 LALSMGYGLLTLQGSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSD 171
            .   :|.|||...|..|..:|....|||....|..:.......|.::.......||: |.::..:
plant   140 F---IGRGLLMANGEAWHHQRHMAAPAFTRDRLKGYAKHMVECTKMMAERLRKEVGE-EVEIGEE 200

  Fly   172 LIRWSFAIATQTTLGTDVTKDDNFENDAILKTYQSMLRLTIINI------FVPFVQNKIVSKLFG 230
            :.|.:..|.::|..|:..  |...|..::|...|.:......::      |:|...|:.:..|
plant   201 MRRLTADIISRTEFGSSC--DKGKELFSLLTVLQRLCAQATRHLCFPGSRFLPSKYNREIKSL-- 261

  Fly   231 LEWLRRRDASAINKMINNILDKKLNS----NPENYCESELKTVIHRAIELFRNDEMSLMELGAEC 291
                    .:.:.:::..|:|.:.:|    ...:|.:..|..:::: ::..:|: :::..:..||
plant   262 --------KTEVERLLMEIIDSRKDSVEIGRSSSYGDDLLGLLLNQ-MDSNKNN-LNVQMIMDEC 316

  Fly   292 SSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTD-------LQQLVY 349
            .:......||::..:.:.|:|||..|..|:.|.:|::         :|...|       |..|..
plant   317 KTFFFTGHETTSLLLTWTLMLLAHNPTWQDNVRDEVR---------QVCGQDGVPSVEQLSSLTS 372

  Fly   350 LDRVLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPEN 414
            |::|:||:|||.|......|...||::|.: ::||||::|.|.:.....:.:.||.:|.:||||.
plant   373 LNKVINESLRLYPPATLLPRMAFEDIKLGD-LIIPKGLSIWIPVLAIHHSNELWGEDANEFNPER 436

  Fly   415 FLPEKI-HDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVI 478
            |..... ..||   |:||:.|.|||||..:.:|.:|:.|..::..:....|..|.:...| .:.|
plant   437 FTTRSFASSRH---FMPFAAGPRNCIGQTFAMMEAKIILAMLVSKFSFAISENYRHAPIV-VLTI 497

  Fly   479 KLAQSPQLAFE 489
            |.....||..:
plant   498 KPKYGVQLVLK 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	106/468 (23%)
CYP735A2	NP_176882.1	PLN02290	2..511	CDD:215164	124/531 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.060