DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a2 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	122/508 - (24%)
Similarity:	223/508 - (43%)	Gaps:	70/508 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IQLLIAASLILW-----IRFLWSRRKL---YMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRTT 60
            :.:.:|..::.|     ::::|.:.|:   |:....|.|....||:|:..:...:.....|....
plant     8 VTVSVAVVVVSWWVWRTLQWVWFKPKMLESYLRRQGLAGTPYTPLVGDLKKNFSMRAEARSKPIN 72

  Fly    61 YMD---------------KHGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALS 110
            ..|               .||.|:..|.|..|.:...||:...:||...:...::.  |..|...
plant    73 LTDDITPRIVPYPLQMLKTHGRTFFTWFGAIPTITIMDPEQITEVLNKVYDFQKAH--TFPLGRL 135

  Fly   111 MGYGLLTLQGSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEK----DVLSD 171
            :..|:|:..|.||...|:.:||||....:.:.:|.|:.....:|..:|..|...|.    ||...
plant   136 IATGVLSYDGDKWAKHRRIINPAFHLEKIKNMVPAFHQSCSEIVCKWDKLVSDKESSCEVDVWPG 200

  Fly   172 LIRWSFAIATQTTLGTDVTKDDN-FENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWL- 234
            |:..:..:.::|..|:...:... ||..|.|   ..::..|:...|:|           |..:|
plant   201 LVSMTADVISRTAFGSSCVEGQRIFELQAEL---AQLIIQTVRKAFIP-----------GYSYLP 251

  Fly   235 ----RRRDASA--INKMINNILDKKLNSNPENYCESE--LKTVIHRAIELFRNDEMSLMELGAEC 291
                ||..|.|  |..::..|::|:|.:.......::  |..::...:...:.:.||..:|..||
plant   252 TKGNRRMKAKAREIQVILRGIVNKRLRAREAGEAPNDDLLGILLESNLGQTKGNGMSTEDLMEEC 316

  Fly   292 SSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHF----PLAKGIEVTHTDLQQLVYLDR 352
            ........||::..:.:.:|||:...:.|.....|:|:.|    |.|:|       |.||..:..
plant   317 KLFYFVGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGDKEPDAEG-------LNQLKVMTM 374

  Fly   353 VLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENF-- 415
            :|.|.|||.|.:|..||...:::.|.: :.:|.|:.|::.|...||:|:.||::|.:|.|:.|
plant   375 ILYEVLRLYPPIPQLSRAIHKEMELGD-LTLPGGVLINLPILLVQRDTELWGNDAGEFKPDRFKD 438

  Fly   416 -LPEKIHDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPY 467
             |.:.  .::..:|.||:.|.|.|||..:.|:.:|:|:..||:.:..:.|..|
plant   439 GLSKA--TKNQASFFPFAWGSRICIGQNFALLEAKMAMALILQRFSFELSPSY 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	114/465 (25%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	120/492 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970