DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp313a2 and CYP709B1

DIOPT Version :9

Sequence 1:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_566092.1	Gene:	CYP709B1 / 819310	AraportID:	AT2G46960	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	543	Identity:	124/543 - (22%)
Similarity:	234/543 - (43%)	Gaps:	96/543 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MIVIQLLIAASLILWIRFLWSRRKLYMLMMQLPGRMGLPLLGNSV---RYLI-------ISRGRM 55
            :::...||...||:.:|..    |.:|:::..|..:...|....:   .|.|       |.:.:.
plant     3 LVIFLALIVLILIIGLRIF----KAFMILVWHPFVLTRRLKNQGISGPNYRIFYGNLSEIKKMKR 63

  Fly    56 SSRTT-------------------YMDKHGSTYMAWIGTTPIVITRDPKIAEKVLTSP--FCINR 99
            .|..:                   :|.::|.|::.|.||.|.:...||::|:.:|::.  |.: :
plant    64 ESHLSILDPSSNDIFPRILPHYQKWMSQYGETFLYWNGTEPRICISDPELAKTMLSNKLGFFV-K 127

  Fly   100 SSQTTNALALSMGYGLLTLQGSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQG 164
            |.....|:.|....||:.::|:.|:..|:.:||||....|.....:.   .|..:.:.:.:..:.
plant   128 SKARPEAVKLVGSKGLVFIEGADWVRHRRILNPAFSIDRLKIMTTVM---VDCTLKMLEEWRKES 189

  Fly   165 EKD-----------------VLSDLIRWSFAIATQTTLGTDVTKDDNFENDAILK-TYQSMLRLT 211
            .|:                 :.:|:|..| |..:....|.:|     |.:...|| .|.:.|...
plant   190 TKEETEHPKIKKEMNEEFQRLTADIIATS-AFGSSYVEGIEV-----FRSQMELKRCYTTSLNQV 248

  Fly   212 II--NIFVPFVQNKIVSKLFGLEWLRRRDASAINKMINNILDKKLNSNPENYCESELKTVIHRAI 274
            .|  ..::|...|..|.|      |.|:..::|.::|::.|..|     .:|.:..|..::....
plant   249 SIPGTQYLPTPSNIRVWK------LERKMDNSIKRIISSRLQSK-----SDYGDDLLGILLKAYN 302

  Fly   275 ELFRNDEMSLMELGAECSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEI-----KEHFPLA 334
            ...:..:||:.|:..||.:......||:::.:.:..:||::..:.||.:..||     ||..|.:
plant   303 TEGKERKMSIEEIIHECRTFFFGGHETTSNLLAWTTMLLSLHQDWQEKLREEIFKECGKEKTPDS 367

  Fly   335 KGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRN 399
            :       ...:|..::.|:.|:|||...|...:||...:::|.: :.||||.|:.|.:.....:
plant   368 E-------TFSKLKLMNMVIMESLRLYGPVSALAREASVNIKLGD-LEIPKGTTVVIPLLKMHSD 424

  Fly   400 TDYWGSEAAQFNPENFLPEKIH-DRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYK-LK 462
            ...|||:|.:|||..|...... ..||.|.:.||.|.|.|||..:.::.:|..|..||:.:: :.
plant   425 KTLWGSDADKFNPMRFANGVSRAANHPNALLAFSVGPRACIGQNFVMIEAKTVLTMILQRFRFIS 489

  Fly   463 TSFPYENLEFVDHMVIKLAQSPQ 485
            ....|::.. ||::.|:    ||
plant   490 LCDEYKHTP-VDNVTIQ----PQ 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	111/487 (23%)
CYP709B1	NP_566092.1	p450	32..517	CDD:299894	116/510 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060