Protein Alignment Cyp313a2 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 560
• Identity: 139/560 - (24%)
• Similarity: 215/560 - (38%)
• Gaps: 167/560 - (29%)

  Fly    15 WIRFLWSR-----------------RKLYMLMMQL-------PGRMGLPLLGNSVRYLIISRGRM 55
            |:...|:|                 .|||:...:|       ||.....|||:.   ..:....|
Mouse     5 WLETRWARPLHLALVFCLALVLMQAMKLYLRRQRLLRDLSPFPGPPAHWLLGHQ---KFLQEDNM 66

  Fly    56 SSRTTYMDKHGSTYMAWIGT------------TPIVITR-DPKI--AEKVLTSPFCINRSSQTTN 105
            .:....:.||...:..|:|.            ..|.::| |||:  ..::||.  ||.|
Mouse    67 ETLDEIVKKHPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKMQYLHQLLTP--CIGR------ 123

  Fly   106 ALALSMGYGLLTLQGSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLS 170
                    |||.|.|.:|...|..:.|||              ..|:|....|:..    ..|..
Mouse   124 --------GLLNLDGPRWFQHRCLLTPAF--------------HQDILKPCVDTMA----HSVKV 162

  Fly   171 DLIRWSFAIATQ-TTLGTDVTKDDNFEN------DAILK-------------TYQSMLRLTIINI 215
            .|.:|.....|| ||:       :.||:      |.|:|             ||:|.::.|
Mouse   163 MLDKWEKMWTTQETTI-------EVFEHINLMTLDIIMKCAFGQETNCQINGTYESYVKAT---- 216

  Fly   216 FVPFVQNKIVSKLFGLEWLRRRDASAINKMINNILDKKLNSNPENYCESELKTVIHRAIELFRND 280
               |...:|:|......|..           ::|:.|   .:|:.:|..||..|||:..|....|
Mouse   217 ---FELGEIISSRLYNFWHH-----------HDIIFK---LSPKGHCFQELGKVIHQYTEKIIQD 264

  Fly   281 EMSLM---------------------------------ELGAECSSMVLAAFETSAHTVYYALVL 312
            ...::                                 :|.||.::.:.|..:.||.::.:.|..
Mouse   265 RKKILKNQVKQDDTQTSQIFLDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDASAASISWLLYC 329

  Fly   313 LAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRETLEDLRL 377
            ||:.||||:....||:.  .|..|..:|...|.::.|....:.|||||:|.||..|||..:.|.|
Mouse   330 LALNPEHQDRCRTEIRS--ILGDGSSITWEQLDEMSYTTMCIKETLRLIPPVPSISRELSKPLTL 392

  Fly   378 SNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFSKGKRNCIGWR 442
            .:|..:|.|||:.:.|:....|...| ::...|:|..|..|....|||.||:|||.|.|||||.:
Mouse   393 PDGHSLPAGMTVVLSIWGLHHNPAVW-NDPKVFDPLRFTKENSDQRHPCAFLPFSSGPRNCIGQQ 456

  Fly   443 YGLMSSKLALVKILRNYKLK---TSFPYENLEFVDHMVIK 479
            :.::..|:|:..||.::::.   |..|    .|..|.|::
Mouse   457 FAMLELKVAIALILLHFQVAPDLTRPP----AFSSHTVLR 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	124/485 (26%)
Cyp4x1	NP_001003947.1	CYP4B-like	66..500	CDD:410771	127/496 (26%)