DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a2 and Cyp4f16

DIOPT Version :9

Sequence 1:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001343232.1	Gene:	Cyp4f16 / 70101	MGIID:	1917351	Length:	524	Species:	Mus musculus

Alignment Length:	496	Identity:	117/496 - (23%)
Similarity:	197/496 - (39%)	Gaps:	76/496 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IAASLILWIRFLWSRRKLYMLMMQLP------GRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHG 66
            |.|.::.|....:..........|.|      |.:|:.........|:...|:     |:.|.|
Mouse    30 ILARILAWTYSFYENCSRLSCFPQPPKKNWFSGHLGMIQSNEEGMQLVTEMGQ-----TFQDVH- 88

  Fly    67 STYMAWIG-TTPIVITRDPKIAEKVLTSPFCINRSSQT-TNALALSMGYGLLTLQGSKWMARRKH 129
               :.|:| ..|::...||.....:|.:|..:.....| ...|...:|.||....|.||...|:.
Mouse    89 ---LFWLGPVIPVLRIVDPAFVAPLLQAPALVAPKDMTFLRFLKPWLGDGLFLSSGDKWSRHRRL 150

  Fly   130 MNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDV----------LSDLIRWSFAIATQTT 184
            :.|||...:|..::.|||...:::.:.:.....:|...:          |..|.:..|..
Mouse   151 LTPAFHFDILKPYVKIFNQSVNIMHAKWKHLSSEGSARLEMFEHISLMTLDSLQKCLFGF----- 210

  Fly   185 LGTDVTKDDNFEN------DAILKTYQSMLRLTI-INIFVPFVQNKIVSKLFGLEWLRRRDASAI 242
                   |.|.:.      .|||:....:::.:: :.:||.|:            :....|....
Mouse   211 -------DSNCQESPSEYISAILELSSLIIKRSLQLFLFVDFL------------YYHTADGRRF 256

  Fly   243 NK---MINNILDKKL--------NSNPENYCESELKTVIHRAIELF------RNDEMSLMELGAE 290
            .|   :::|..|..:        :.|.:.:.:|:.|:.....|::.      ...|:|..::.||
Mouse   257 RKACDLVHNFTDAVIRERRHTLSSQNHDEFLKSKTKSKTLDFIDVLLLAKDEHGKELSDEDIRAE 321

  Fly   291 CSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLN 355
            ..:.:....:|:|..:.:.|..||..||:||....|::|.....:..|:...||.||.:|...:.
Mouse   322 ADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRDREPEEIEWDDLAQLPFLTMCIK 386

  Fly   356 ETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKI 420
            |:|||...|....|....|:.|.:|.|||||....|.||....|...| .:...::|..|.||..
Mouse   387 ESLRLHSPVIDLLRRCTRDIVLPDGRVIPKGNICVISIFGIHHNPSVW-PDPEVYDPFRFDPENP 450

  Fly   421 HDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKL 461
            ..|.|.||||||.|.|||||..:.:...|:||...|..:::
Mouse   451 QKRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRI 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	113/471 (24%)
Cyp4f16	NP_001343232.1	p450	52..514	CDD:306555	114/474 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820