Protein Alignment Cyp313a2 and CYP4F12

DIOPT Version :9

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_076433.3
• Gene: CYP4F12 / 66002
• HGNCID: 18857
• Length: 524
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 130/529 - (24%)
• Similarity: 210/529 - (39%)
• Gaps: 102/529 - (19%)

  Fly     1 MIVIQLLIAASLILWIRFLWSRRKLYMLMMQLP------GRMGLPLLGNSVRYLIISRGRMSSRT 59
            ::|:...:.|.::.|....::..:......|.|      |.:||         :..:...:.:.|
Human    23 LLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGL---------ITPTEEGLKNST 78

  Fly    60 TYMDKHGSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALS-----------MGY 113
            .....:...:..|:|  ||:    |.|   ||..|..|...:..:.|:|..           :|.
Human    79 QMSATYSQGFTVWLG--PII----PFI---VLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGE 134

  Fly   114 GLLTLQGSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEK------------ 166
            |:|...|.||...|:.:.|||..::|.|::.|||...::::..:.....:|..
Human   135 GILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMT 199

  Fly   167 -DVLSDLI---------RWSFAIATQTTLGTDVTKDDNFENDAILKTYQSMLRLT---------- 211
             |.|...|         |.|..|||...|...|.|    .:..||:....:..|:
Human   200 LDSLQKCIFSFDSHCQERPSEYIATILELSALVEK----RSQHILQHMDFLYYLSHDGRRFHRAC 260

  Fly   212 -IINIFVPFVQNKIVSKLFGLEWLRRRDASAINKMINNILDKKLNSNPENYCESELKTVIHRAIE 275
             :::.|...|             :|.|..:...:.|::....|..|          ||:....:.
Human   261 RLVHDFTDAV-------------IRERRRTLPTQGIDDFFKDKAKS----------KTLDFIDVL 302

  Fly   276 LFRNDE----MSLMELGAECSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKG 336
            |...||    :|..::.||..:.:....:|:|..:.:.|..||..||:||....|::|.......
Human   303 LLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDP 367

  Fly   337 IEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTD 401
            .|:...||.||.:|...:.|:|||.|..||.||...:|:.|.:|.|||||:|..|||.....|..
Human   368 KEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPT 432

  Fly   402 YWGSEAAQFNPENFLPEKIHDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSF- 465
            .| .:...::|..|.||....|.|.||||||.|.|||||..:.:...|:.|..:|.:::.....
Human   433 VW-PDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHT 496

  Fly   466 -PYENLEFV 473
             |...||.:
Human   497 EPRRKLELI 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	123/483 (25%)
CYP4F12	NP_076433.3	p450	52..506	CDD:306555	127/500 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810