Protein Alignment Cyp313a2 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 506
• Identity: 126/506 - (24%)
• Similarity: 229/506 - (45%)
• Gaps: 50/506 - (9%)

  Fly     4 IQLLIAASLILWIRFLWSRRKLYML---------MMQLPGRMGLPLLGNSVRYLIISRGRMSSRT 59
            ::|:...|:..|:..:.|....|:.         .:.:||...|||.||.:.||   .|......
Mouse     1 MELIPNLSIQTWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGNIINYL---DGMWKFDD 62

  Fly    60 TYMDKHGSTYMAWIGTTPIVITRDPKIAEKVLT----SPFCINRSSQTTNALALSMGYGLLTL-Q 119
            ....|:|..:..:.|..||:...||:|.:.||.    |.|...|.......|..|     :|: :
Mouse    63 DCYKKYGKIWGFYEGPQPILAIMDPEIIKIVLVKECYSVFTNRRPFGPVGFLKKS-----ITISE 122

  Fly   120 GSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLI-RWSFAIATQT 183
            ..:|...|..::|.|..|.|....||.....|:||........:.|...:.|:. .:|..:.|.|
Mouse   123 DEEWKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYSMDVITGT 187

  Fly   184 TLGTDVTKDDNFENDAILKTYQSMLRLTIINIFVPFVQNKI-------VSKLFGLEWLRRRDASA 241
            :.|.::...:|.::..:    |.:.::.....|.||:.:.:       :.::..|....|:..:.
Mouse   188 SCGVNIDSLNNPQDPFV----QKIKKILKFKFFDPFLLSVVLFPFLTPIYEMLNLSIFPRQSMNF 248

  Fly   242 INKMINNILDKKLNSNPEN---YCESELKTVIHRAIELFRNDEMSLMELGAECSSMVLAAFETSA 303
            ..|.:..:...:|:.|.:|   :.:..:.|...:..|..:  .:|.:|:.|:....:...::.::
Mouse   249 FKKFVKKMKKDRLDYNQKNRVDFLQLMMNTQNSKGQESLK--ALSDLEMAAQTLIFIFGGYDGTS 311

  Fly   304 HTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSS 368
            .::.:.:..||..|:.|:.:.:||....|  ....||:..|..:.|||.|:||:|||.|.|....
Mouse   312 TSISFIMYELATHPDVQKKLQDEIDRALP--NKAPVTYDALMDMEYLDMVVNESLRLYPVVSRID 374

  Fly   369 RETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFSK 433
            |.:.:|:.: :||.||||..:.|.|:...|:.:|| .|...|.||.|..|...:..||.::||..
Mouse   375 RFSKKDVEI-HGVFIPKGTIVMIPIYPLHRDPEYW-PEPEDFCPERFSKENKGNIDPYIYMPFGN 437

  Fly   434 GKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSP 484
            |.|||||.|:.|:|.|||:..:|:|:.::   |.|..:    :.:|:::.|
Mouse   438 GPRNCIGMRFALISVKLAVTGVLQNFTVQ---PCEETQ----IPVKISRQP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	110/435 (25%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	111/437 (25%)