Protein Alignment Cyp313a2 and cyp46a1.3

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 506
• Identity: 126/506 - (24%)
• Similarity: 221/506 - (43%)
• Gaps: 100/506 - (19%)

  Fly     6 LLIAASLILWIRFLWSRRKLYMLMMQLPGRMGLP-----LLGNSVRYLIISRGRMSSRTTYMDKH 65
            ||:|..||.::.|......::|....:||    |     .||:|...|     |:......|..|
 Frog    13 LLLALILICFLLFSGYIHYIHMKYDHIPG----PPRDSFFLGHSPTML-----RLMKNNLLMYDH 68

  Fly    66 GSTYMAWIGT-----------TPIVITRDPKIAEKVLTSPFCINRSSQ------TTNALALS-MG 112
               ::.|:..           ..|::...|:..:::|.||    :.|:      ..|...:. ||
 Frog    69 ---FLGWVQKYGPVVRINGLHRVIILVVSPEAVKELLMSP----KYSKDKFYDVIANMFGVRFMG 126

  Fly   113 YGLLTLQG-SKWMARRKHMNPAFKHSVLLSFLPIFNAET-DLLVSVFDSFVGQGEKDVLSDLIRW 175
            .||:|.:. ..|..:|:.|:|||..:.|:..:..||.:. :|:..:.:...|:.|..:...|.|.
 Frog   127 KGLVTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKADGKCEIKMHDMLSRL 191

  Fly   176 SFAIATQTTLGTDVTKDDNFEND--------------AILKTYQSMLRLTIINI-FVPFVQNKI- 224
            :..:..:...|.::    |..||              .|::....|:|.::... |:..||..|
 Frog   192 TLDVIGKVAFGMEL----NSLNDDLTPFPKAISLVMKGIVEMRNPMVRYSLAKRGFIRKVQESIR 252

  Fly   225 VSKLFGLEWLRRRDASAINKMIN-------NILDKKL-NSNPENYCESELKTVIHRAIELFRNDE 281
            :.:..|.|.:.||     .|.|.       :||.:.| .:..|..|:.|:  ::...:..|
 Frog   253 LLRQTGKECIERR-----QKQIQDGEEIPVDILTQILKGAAMEEECDPEI--LLDNFVTFF---- 306

  Fly   282 MSLMELGAECSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQ 346
                          :|..||:|:.:.:.::.|...||..|....||.|.....:.||  :.||.:
 Frog   307 --------------IAGQETTANQLSFVVMELGRNPEILEKAQAEIDEVIGSKRDIE--YEDLGK 355

  Fly   347 LVYLDRVLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFN 411
            |.||.:||.|||||.|:.|.:||...||: :.:||.:|:.:||.::.:...|...|: |:...||
 Frog   356 LQYLSQVLKETLRLYPTAPGTSRGLTEDM-VIDGVKVPENVTIMLNSYIMGRMEQYY-SDPLTFN 418

  Fly   412 PENFLPEKIHDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLK 462
            |:.|.|:.  .:..|::.|||.|.|:|||..:..|.:|:.:.|:|:.|:.:
 Frog   419 PDRFSPDA--PKPYYSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYEFE 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	109/441 (25%)
cyp46a1.3	NP_001027517.1	CYP46A1-like	66..490	CDD:410706	110/444 (25%)