Protein Alignment Cyp313a2 and CYP4F11

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_067010.3
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 490
• Identity: 121/490 - (24%)
• Similarity: 212/490 - (43%)
• Gaps: 49/490 - (10%)

  Fly     3 VIQLLIAASLIL-----WIRFLWSRRKLYMLMMQLP------GRMGLPLLGNSVRYLIISRGRMS 56
            ::.||:..|.:|     |....:...:......|.|      |..||         :..:...|.
Human    20 LLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWFWGHQGL---------VTPTEEGMK 75

  Fly    57 SRTTYMDKHGSTYMAWIGTT-PIVITRDPKIAEKVLTSPFCINRSSQT-TNALALSMGYGLLTLQ 119
            :.|..:..:...:..|:|.| |::|...|.|...:.::...:...... ...|...:|.|||...
Human    76 TLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSG 140

  Fly   120 GSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTT 184
            |.||...|:.:.|||..::|..::.|||...:::...:.....:|...:  |:.. ..::.|..:
Human   141 GDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQRLASEGSARL--DMFE-HISLMTLDS 202

  Fly   185 LGTDVTKDDNFENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWLR------RRDASAIN 243
            |...|.   :||::...|..:.:..:..::.||.....:|:.....|.:|.      ||....::
Human   203 LQKCVF---SFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVH 264

  Fly   244 KMINNILDKKLNSNP--------ENYCESELKTVIHRAIELFRND----EMSLMELGAECSSMVL 296
            ...:.::.::..:.|        :|..:|  ||:....:.|...|    |:|..::.||..:.:.
Human   265 DFTDAVIQERRCTLPTQGIDDFLKNKAKS--KTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMF 327

  Fly   297 AAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLM 361
            ...:|:|..:.:.|..||..||:||....|::|.....:.||:...||.||.:|...:.|:|||.
Human   328 EGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLH 392

  Fly   362 PSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPY 426
            |.||..||...:|..|.:|.|||||:...|:|.....|...| .:...::|..|..|.|.:|.|.
Human   393 PPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRFDQENIKERSPL 456

  Fly   427 AFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKL 461
            ||||||.|.|||||..:.:...|:.|...|.::::
Human   457 AFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	109/416 (26%)
CYP4F11	NP_067010.3	CYP4F	74..515	CDD:410772	111/427 (26%)