Protein Alignment Cyp313a2 and Cyp3a25

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 511
• Identity: 131/511 - (25%)
• Similarity: 226/511 - (44%)
• Gaps: 74/511 - (14%)

  Fly     6 LLIAASLILWIRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGSTYM 70
            :|:..||:|:..:......|:. .:.:||...|||||....|.   .|..........|:|..:.
Mouse    13 VLLVTSLVLFYIYGTYSHGLFK-KLGIPGPKPLPLLGTIFNYY---DGMWKFDEDCYKKYGKIWG 73

  Fly    71 AWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTN------------ALALSMGYGLLTLQGSKW 123
            .:.|..||:...||:|.:.||... |.   |..||            |:.:|        :..:|
Mouse    74 FYEGPQPILAIMDPEIIKIVLVKE-CY---SVFTNRRFFGPVGFMKKAITIS--------EDEEW 126

  Fly   124 MARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLI-RWSFAIATQTTLGT 187
            ...|..::|.|....|....||.....|:||........:||...:.|:. .:|..:.|.|:.|.
Mouse   127 KRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSMDVITGTSFGV 191

  Fly   188 DVTKDDNFEN--DAILKTYQSMLRLTIINIFVPFVQNKI-------VSKLFGLEWLRRRDASAIN 243
            :|   |:..|  |..::..:.:|:   ..||.||:.:.|       :.::.......|...:...
Mouse   192 NV---DSLNNPQDPFVQKAKKILK---FKIFDPFLLSIILFPFLTPIYEMLNFSIFPRDSMNFFK 250

  Fly   244 KMINNILDKKLNSNPENYCESELKTVIHRAIELFRNDE----------MSLMELGAECSSMVLAA 298
            |.:..:..::|.||.:|..:         .::|..|.:          :|.:|:.|:....:...
Mouse   251 KFVKRMKKERLASNQKNRVD---------FLQLMMNTQNSKGQESQKALSDLEMAAQAVIFIFGG 306

  Fly   299 FETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPS 363
            ::.::.::...:..||..|:.|:.:.:||....|  ....||:..|..:.|||.|:||:|||.|.
Mouse   307 YDATSTSISLIMYELATHPDVQKKLQDEIDRTLP--NKAPVTYDALMDMEYLDMVVNESLRLYPI 369

  Fly   364 VPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAF 428
            .....|.:.:|:.: |||.||||..:.|.|:...||.:|| .|..:|.||.|..|...:..||.:
Mouse   370 AIRLERVSKKDVEI-NGVFIPKGTVVMIPIYPLHRNPEYW-PEPQEFCPERFSKENKGNIDPYIY 432

  Fly   429 IPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSP 484
            :||..|.|||||.|:.|:|.|||::.:|:|:.::   |.|..:    :.:|:::.|
Mouse   433 MPFGNGPRNCIGMRFALISIKLAVIGVLQNFTVQ---PCEETQ----IPLKISREP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	116/451 (26%)
Cyp3a25	NP_062766.2	CYP3A	67..492	CDD:410743	117/453 (26%)