DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a2 and cyp3c2

DIOPT Version :9

Sequence 1:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	XP_021330384.1	Gene:	cyp3c2 / 558473	ZFINID:	ZDB-GENE-081103-62	Length:	503	Species:	Danio rerio

Alignment Length:	513	Identity:	122/513 - (23%)
Similarity:	226/513 - (44%)	Gaps:	59/513 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLIAASLILWIRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGSTYM 70
            |::....:|::..:|...  :...:.:||....|..|..:.|   ::|..:.......|:|..:.
Zfish    13 LVVLVLTLLYMYGVWPHG--FFKKLGIPGPRPWPFFGTFLSY---TKGFFNFDMECAKKYGKVWG 72

  Fly    71 AWIGTTPIVITRDPKIAEKVLT----SPFCINRSSQTTNALALSMGYGLLTLQGSKWMARRKHMN 131
            .:.|..||::..|.::.:.::.    |.|...|.....  ||..:..|:..::..:|...|..::
Zfish    73 IYDGRLPILMVTDLEMIKTIMVKECYSTFTNRREINVD--LAGPLADGITAVKDERWKRIRGTLS 135

  Fly   132 PAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGE-----KDVLSDLIRWSFAIATQTTLGTDVTK 191
            |.|....|....||.....|..:.....  |..|     |:|::.   :|..:.|.:....|:..
Zfish   136 PYFTSGRLKEIFPIAMTHADRFIKNMQK--GDHEQPVKIKEVMAS---YSLDVVTSSAFSVDIDS 195

  Fly   192 DDNFENDAILKTYQSMLRLTIINIFV------PFVQNKIVSKLFGLEWLRRRDASAINKMINNIL 250
            .:| .:|..:...::.|:..:..:||      |.:.| ::.|: ||....:.......|.:..|.
Zfish   196 INN-PDDPFVTNIKNFLKFNLFGLFVLLLTVFPSIAN-LLGKM-GLSMFSKPTVDFFYKALRKIK 257

  Fly   251 DKKLNSN----------PENYCESELKTVIHRAIELFRNDEMSLMELGAECSSMVLAAFETSAHT 305
            ::..:||          .....:.::|.......|....|.    |:.::....::..:||::.|
Zfish   258 EEHKDSNGRVDFFRLMIQNEIPDDQVKDTTSEQPEKGLTDH----EILSQSFIFIMGGYETTSTT 318

  Fly   306 VYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSR- 369
            :.:.|..||:.|:..|.:..:|.::|||  ...:::..|.::.||:..:||::||:|:.|...|
Zfish   319 LTFLLYNLAINPDCLEKLVEKIDKNFPL--DTPISYDALMKIDYLEMSINESMRLLPTAPRLERV 381

  Fly   370 --ETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFS 432
              :|:|    .||:.|||...|:|..:...::...|.| ..:|.||.|.||...:...|||:||.
Zfish   382 CKKTVE----MNGITIPKDTMITIPTYVLNQDPQLWDS-PHEFRPERFSPENKSEFLQYAFMPFG 441

  Fly   433 KGKRNCIGWRYGLMSSKLALVKILRNYKL----KTSFPYE-NLEFVDHMVIKLAQSPQ 485
            .|.|||||.||.||..||.:||:|:|:.:    :|..|.| |..|...:.|.|..:|:
Zfish   442 LGPRNCIGMRYALMIVKLLVVKLLQNFSVETCKETQIPLELNPVFQPKVPITLKLTPR 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	111/461 (24%)
cyp3c2	XP_021330384.1	p450	38..496	CDD:306555	118/481 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010