Protein Alignment Cyp313a2 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001098671.1
• Gene: Cyp26c1 / 546726
• MGIID: 2679699
• Length: 518
• Species: Mus musculus
• Alignment Length: 492
• Identity: 120/492 - (24%)
• Similarity: 199/492 - (40%)
• Gaps: 60/492 - (12%)

  Fly     6 LLIAASLILWIRFLWSRRKLYMLMMQLP-GRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGSTY 69
            ||:..:..|| ...|:..:.:...:.|| |.||.|..|.::.:|:......|||   .:::|:.:
Mouse    24 LLLGLAQQLW-TLRWTLSRDWASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSR---RERYGTVF 84

  Fly    70 MAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQGSKWMARRKHMNPAF 134
            ...:...|::.....:....:|.....:.||....:|..|...:.||...|.....|||.:...|
Mouse    85 KTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRQRRKVLARVF 149

  Fly   135 KHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTTLGTDVTKDDNFENDA 199
            ..|.|..|:|  ..:..|...|......|....|.......:|.:|.:..||..:   |......
Mouse   150 SRSSLEQFVP--RLQGALRREVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQL---DEARCTE 209

  Fly   200 ILKTYQSMLRLTIINIF-----VPFVQNKIVSKLFGL-EWLRRRDA--SAINKMINNILDKKLNS 256
            :..|::.::.    |:|     |||         .|| :.:|.||.  ..:::.:...|.:|..:
Mouse   210 LAHTFEQLVE----NLFSLPLDVPF---------SGLRKGIRARDQLYEHLDEAVAEKLQEKQTA 261

  Fly   257 NPENYCESELKTVIHRAIELFRNDEMSLMELGAECSSMVLAAFETSAHTVYYALVLLAMFPEHQE 321
            .|.:    .|..:|:.|.||  ..|.|:.||......::.|||.|:|......::||...|....
Mouse   262 EPGD----ALLLIINSAREL--GHEPSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAIT 320

  Fly   322 MVFNEIKEH--------FPLAKGI--------EVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRE 370
            .:..|:...        .|.|.|.        :::...|.:|.|:|.|:.|.|||:|.|....|.
Mouse   321 KIQQELSAQGLGRACTCTPRASGSPPDCGCEPDLSLAMLGRLRYVDCVVKEVLRLLPPVSGGYRT 385

  Fly   371 TLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHP---YAFIPFS 432
            .|....| :|..||||.::...|.:|......:.|....|:||.|..|....|..   :.:|||.
Mouse   386 ALRTFEL-DGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESGDARGSGGRFHYIPFG 449

  Fly   433 KGKRNCIGWRYGLMSSKLALVKILR--NYKLKT-SFP 466
            .|.|:|:|........:|..|:::|  .::|.| :||
Mouse   450 GGARSCLGQELAQAVLQLLAVELVRTARWELATPAFP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	104/431 (24%)
Cyp26c1	NP_001098671.1	cytochrome_P450	59..504	CDD:477761	109/456 (24%)