Protein Alignment Cyp313a2 and CYP4F3

DIOPT Version :9

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 125/510 - (24%)
• Similarity: 211/510 - (41%)
• Gaps: 89/510 - (17%)

  Fly     3 VIQLLIAASLILWIRFLWS-----------------RRKLYMLMMQLPGRMGLPLLGNSVRYLII 50
            ::.||:.||.:|.....|:                 :|..::      |.:|  |:.:|...|:.
Human    20 LLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWFL------GHLG--LIHSSEEGLLY 76

  Fly    51 SRGRMSSRTTYMDKHGSTYMAWIGT-TPIVITRDPKIAEKVLTSPFCI-NRSSQTTNALALSMGY 113
            ::   |...|:    |.....|:|. ..||....|...:.||.:|..| .:.....:.|...:|.
Human    77 TQ---SLACTF----GDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPWLGD 134

  Fly   114 GLLTLQGSKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDV---------- 168
            |||...|.||...|:.:.|||..::|..::.|||...:::.:.:.....:|...:
Human   135 GLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARLDMFEHISLMT 199

  Fly   169 LSDLIRWSFA------------IATQTTLGTDVTKDDNFENDAILKTYQSMLRLTIINIFVPFVQ 221
            |..|.:..|:            ||....|...|||          :..|.:|.:..:....|..|
Human   200 LDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTK----------RHQQILLYIDFLYYLTPDGQ 254

  Fly   222 NKIVSKLFGLEWLRRRDASAINKMINNILDKKLNSNPEN------YCESELKTVIHRAIELFRND 280
            .            .||....::...:.::.::..:.|..      ..:::.||:....:.|...|
Human   255 R------------FRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKD 307

  Fly   281 E----MSLMELGAECSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTH 341
            |    :|..::.||..:.:....:|:|..:.:.|..||..||:||....|::|.....:..|:..
Human   308 EDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEW 372

  Fly   342 TDLQQLVYLDRVLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSE 406
            .||.||.:|...:.|:|||.|.||..||...:|:.|.:|.|||||:...|.:|.|..|...| .:
Human   373 DDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PD 436

  Fly   407 AAQFNPENFLPEKIHDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKL 461
            ...::|..|.|:.|.:|.|.||||||.|.|||||..:.:...|:.|...|..:::
Human   437 PEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	118/463 (25%)
CYP4F3	NP_000887.2	p450	52..515	CDD:365848	119/478 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810