DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a2 and Cyp312a1

DIOPT Version :9

Sequence 1:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_001262008.1	Gene:	Cyp312a1 / 40005	FlyBaseID:	FBgn0036778	Length:	510	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	113/516 - (21%)
Similarity:	232/516 - (44%)	Gaps:	64/516 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LIAASLILWIRFLWSRR-KLYMLMMQLPGRMGLPLLGN-SVRYLIISRGRMSSRTTYMDKHGSTY 69
            |:..:|.|::.:::.|: ::..|..:.|....||.:|: .:...::....:...|..:::|...:
  Fly     8 LLLLALSLYLLYVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLRRATEMINEHLHDH 72

  Fly    70 MA--WIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGY---GLLTLQGSKWMARRKH 129
            .|  |:||...::..:||..:.:.::    .:..|.||...:...:   ||.|....||..|||.
  Fly    73 RAKLWMGTKLYLVDCNPKDIQALCSA----QQLLQKTNDYRVFENWLCEGLFTSGFEKWSHRRKI 133

  Fly   130 MNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEK-DVLSDLIRWSFAIATQTTLGTDVTKDD 193
            :.|||.::::..|:.:|..::.:|::....|...|:: |.|..:..::.....:|.||..|....
  Fly   134 VMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAESGDQIDFLQLISCFTLDTICETALGVSVGSQS 198

  Fly   194 NFENDAI--LKTYQSMLRLTIINIFV--PFV---------QNKIVSKLFGLEWLRRRDASAINKM 245
            :.:::.:  :|:...::...:.|||.  .|:         :.:::..|.|.      ....|.|.
  Fly   199 SAKSEYLDAVKSILVIIDKRLKNIFYRNSFIFKRTSHYKREQELIKTLHGF------TEGIIQKR 257

  Fly   246 INNILDKKLNSNPENYCESELKTVIHR-----AIELFRNDE---MSLMELGAECSSMVLAAFETS 302
            |:.|.....|.|.:: .::||..|...     .:.|.:..:   :::.::..|..:::...|:.:
  Fly   258 IDEINQDAENRNYQS-SDAELDGVKRTLCFLDTLLLSKGPDGKPLTVKDIREEVDTIIFGGFDLT 321

  Fly   303 AHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFS 367
            |.|:.:.:..:.:.||||:....|:.......|...::...::||.:|:..:.||||:.||.|.:
  Fly   322 ATTLNFFMYNMTLHPEHQQRCREEVWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLT 386

  Fly   368 SRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFS 432
            :|:...:..: |...||||..:.|......|..|:: .:...|.|:.:............||||.
  Fly   387 ARKATANCTI-NDFFIPKGSDVIISPIYMGRCKDFF-PDPMVFKPDRWAIGAEPKIEATTFIPFM 449

  Fly   433 KGKRNCIGWRYGLMSSKLALVKILRNY----------KLKTSF--------PY----ENLE 471
            .|.|:|:|.||.::..|:.|..:|||:          |||.:|        ||    :||:
  Fly   450 AGARSCMGQRYAMVMLKMVLAHLLRNFLFEPLGERQVKLKLNFVITLHTVEPYLCRAKNLD 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	102/467 (22%)
Cyp312a1	NP_001262008.1	p450	35..505	CDD:278495	106/482 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.870