Protein Alignment Cyp313a2 and Cyp3a44

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_796354.1
• Gene: Cyp3a44 / 337924
• MGIID: 2449818
• Length: 504
• Species: Mus musculus
• Alignment Length: 493
• Identity: 128/493 - (25%)
• Similarity: 216/493 - (43%)
• Gaps: 56/493 - (11%)

  Fly     4 IQLLIAASLILWIRFLWSRRKLYMLMMQ-LPGRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGS 67
            :..|:..::||.:.:.:..|...:...| :||...||.||..:.|.   .|.........:|:|.
Mouse     9 LDTLVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYY---TGIWKFDMECYEKYGK 70

  Fly    68 TYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALS----MGYGLLTLQGSKWMARRK 128
            |:..:.|.||:::..||:..:.||... |:   |..||.....    |...:...:..:|...|.
Mouse    71 TWGLFDGQTPLLVITDPETIKNVLVKD-CL---SVFTNRREFGPVGIMSKAISISKDEEWKRYRA 131

  Fly   129 HMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLI-RWSFAIATQTTLGTDVTKD 192
            .::|.|....|....|:.....|:||........:|....:.|:: .:|..:.|.|:.|.:|...
Mouse   132 LLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEAEKGMPVAMKDVLGAYSMDVITSTSFGVNVDSL 196

  Fly   193 DNFENDAILKTYQSMLRLTIINIFVPFVQNKI-------VSKLFGLEWLRRRDASAINKMINNIL 250
            :|.| |..::..:..||   ::.|.|.:.:.:       |.::..:............|.::.:.
Mouse   197 NNPE-DPFVEEAKKFLR---VDFFDPLLFSVVLFPLLTPVYEMLNICMFPNDSIEFFKKFVDRMQ 257

  Fly   251 DKKLNSNPENYCESELKTVIHRA--IELFRNDE-----------MSLMELGAECSSMVLAAFETS 302
            :.:|:||.:           ||.  ::|..|..           .|.||:..:....:.|.:||:
Mouse   258 ESRLDSNQK-----------HRVDFLQLMMNSHNNSKDKDSHKAFSNMEITVQSIIFISAGYETT 311

  Fly   303 AHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFS 367
            :.|:.:.|..||..|:.|:.:..||.:..| .|......| :.::.|||.||||||||.|.|...
Mouse   312 SSTLSFTLYCLATHPDIQKKLQAEIDKALP-NKATPTCDT-VMEMEYLDMVLNETLRLYPIVTRL 374

  Fly   368 SRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFS 432
            .|...:|:.| |||.||||..:.|..:....:..:| .:..:|.||.|..|......||.::||.
Mouse   375 ERVCKKDVEL-NGVYIPKGSMVMIPSYALHHDPQHW-PDPEEFQPERFSKENKGSIDPYVYLPFG 437

  Fly   433 KGKRNCIGWRYGLMSSKLALVKILRNYKL----KTSFP 466
            .|.|||||.|:.||:.|||:.|:|:|:..    :|..|
Mouse   438 IGPRNCIGMRFALMNMKLAVTKVLQNFSFQPCQETQIP 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	114/430 (27%)
Cyp3a44	NP_796354.1	CYP3A	67..493	CDD:410743	115/432 (27%)