DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a2 and Cyp4d1

DIOPT Version :9

Sequence 1:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_476907.2	Gene:	Cyp4d1 / 31188	FlyBaseID:	FBgn0005670	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	132/508 - (25%)
Similarity:	222/508 - (43%)	Gaps:	79/508 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 IVIQLLIAASLILWIRFLWSR-RKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRT-TYMDK 64
            :||..::|::|.:.:.....: ::|..|:..:||...|||:|:...::......|..:. .:|:.
  Fly     3 LVIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFMET 67

  Fly    65 HGSTYM--AWIGTTPIVITRDPKIAEKVL-TSPFCINRSSQTTNALALSMGYGLLTLQGSKWMAR 126
            :....:  .|:|....|:..:||..|.|| |..|  |..:....||...:..|||..:|.||..|
  Fly    68 YSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRF--NDKAGEYKALEPWLKEGLLVSRGRKWHKR 130

  Fly   127 RKHMNPAFKHSVLLSFLPIF-NAETDLLVSVFDSFVGQGEKDVLSDLIRW----SFAIATQTTLG 186
            ||.:.|||...:|..|:.:| ....|||.::....:..|:...  .|..|    :.....:|.:|
  Fly   131 RKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGF--SLYDWINLCTMDTICETAMG 193

  Fly   187 TDVTKDDNFENDAI--LKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWLRRRDASAINKMINNI 249
            ..:....|.:::.:  :||...:|...:.||...|      ...:.|..|.|.:..|:|.:
  Fly   194 VSINAQSNADSEYVQAVKTISMVLHKRMFNILYRF------DLTYMLTPLARAEKKALNVL---- 248

  Fly   250 LDKKLNSNPENYCESELKTVIHRAIELFR--------NDE------------------------M 282
                     ..:.|   |.::.|..||.|        ||:                        :
  Fly   249 ---------HQFTE---KIIVQRREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPL 301

  Fly   283 SLMELGAECSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQL 347
            |.:::..|..:.:....:|::..:.:....:|..||.|:..|.||:......|...|::..|.||
  Fly   302 SNLDIREEVDTFMFEGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQL 366

  Fly   348 VYLDRVLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNP 412
            .|:|..:.||||:.||||...|:.|||..: ||.:||.|..|.|......|..:.: ||...|.|
  Fly   367 HYVDLCVKETLRMYPSVPLLGRKVLEDCEI-NGKLIPAGTNIGISPLYLGRREELF-SEPNIFKP 429

  Fly   413 ENF----LPEKIHDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKL 461
            |.|    ..||:   :|||:||||.|.|||||.::.::..|..:..:||:|::
  Fly   430 ERFDVVTTAEKL---NPYAYIPFSAGPRNCIGQKFAMLEIKAIVANVLRHYEV 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	126/476 (26%)
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	126/476 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.860