Protein Alignment Cyp313a2 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: XP_217935.3
• Gene: Cyp26c1 / 308190
• RGDID: 1308843
• Length: 518
• Species: Rattus norvegicus
• Alignment Length: 492
• Identity: 121/492 - (24%)
• Similarity: 204/492 - (41%)
• Gaps: 60/492 - (12%)

  Fly     6 LLIAASLILWIRFLWSRRKLYMLMMQLP-GRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGSTY 69
            ||:..:..|| ...|:..:.:...:.|| |.||.|..|.::.:|:......|||   .:::|:.:
  Rat    24 LLLGLAQQLW-TLRWTLSRDWASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSR---RERYGTVF 84

  Fly    70 MAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQGSKWMARRKHMNPAF 134
            ...:...|::.....:....:|.....:.||....:|..|...:.||...|.:...|||.:...|
  Rat    85 KTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGERHRQRRKVLARVF 149

  Fly   135 KHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTTLGTDVTKDDNFENDA 199
            ....|..|:|  ..:..|...|......|....|.......:|.:|.:..||..:   |......
  Rat   150 SRPALEQFVP--RLQEALRREVRSWCAAQRPVAVYQAAKALTFRMAARILLGLQL---DEARCTE 209

  Fly   200 ILKTYQSMLRLTIINIF-----VPFVQNKIVSKLFGL-EWLRRRDA--SAINKMINNILDKKLNS 256
            :.:|::.::.    |:|     |||         .|| :.:|.||.  ..::::|...|.::|.:
  Rat   210 LAQTFERLVE----NLFSLPLDVPF---------SGLRKGIRARDQLYQHLDEVIAEKLREELTA 261

  Fly   257 NPENYCESELKTVIHRAIELFRNDEMSLMELGAECSSMVLAAFETSAHTVYYALVLLAMFPEHQE 321
            .|.:    .|..:|:.|.||.|  |:|:.||......::.|||.|:|......::||...|....
  Rat   262 EPGD----ALHLIINSARELGR--ELSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAIA 320

  Fly   322 MVFNEIKEH--------FPLAKGI--------EVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRE 370
            .:..|:...        .|.|.|.        :::...|.:|.|:|.|:.|.|||:|.|....|.
  Rat   321 KIQQELSAQGLGSPCSCAPRASGSRPDCSCEPDLSLAVLGRLRYVDCVVKEVLRLLPPVSGGYRT 385

  Fly   371 TLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHP---YAFIPFS 432
            .|....| :|..||||.::...|.:|......:.|....|:||.|..|....|..   :.:|||.
  Rat   386 ALRTFEL-DGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESEDARGSGGRFHYIPFG 449

  Fly   433 KGKRNCIGWRYGLMSSKLALVKILR--NYKLKT-SFP 466
            .|.|:|:|........:|..|:::|  .::|.| :||
  Rat   450 GGARSCLGQELAQAVLQLLAVELVRTARWELATPAFP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	105/431 (24%)
Cyp26c1	XP_217935.3	cytochrome_P450	59..504	CDD:477761	110/456 (24%)