Protein Alignment Cyp313a2 and Cyp4a8

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_113793.2
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 122/499 - (24%)
• Similarity: 209/499 - (41%)
• Gaps: 47/499 - (9%)

  Fly     4 IQLLIAASLILW--IRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHG 66
            |..::...|:|:  .:|...||.|.....|.|........|:.    |..........|.:....
  Rat    21 IATVLTVLLLLFKTAQFYLHRRWLLRATQQFPSPPSHWFFGHK----IPKDQEFQDILTRVKNFP 81

  Fly    67 STYMAWI-GTTPIVITRDPKIAEKVL--TSPFCINRSSQTTNALALSMGYGLLTLQGSKWMARRK 128
            |....|: |:...:...||...:.:|  :.|    :|..:...||..:|||||.|.|..|...|:
  Rat    82 SACPQWLWGSNVRIQVYDPDYMKLILGRSDP----KSHHSYRFLAPWIGYGLLLLNGQTWFQHRR 142

  Fly   129 HMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTTLGTDVTKDD 193
            .:.|||.:..|..::.|......:::..::..|||   |...::.:....:...|.:....:::.
  Rat   143 MLTPAFHYDTLKPYVGIMADSVRIMLDKWEQIVGQ---DSTLEIFQHITLMTLDTIMKCAFSQEG 204

  Fly   194 NFENDAILKTY----QSMLRLTIINIFVPFVQNKIVSKLFGLEWLRRRDASAINKMINNILDKKL 254
            :.:.|...|:|    :.:..|:...|...|.||.|:..|..    ..|.|.:..::.:...|:.:
  Rat   205 SVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSS----NGRKARSAWQLAHEHTDQVI 265

  Fly   255 NS-NPENYCESELKTVIHRA------IELFRNDE----MSLMELGAECSSMVLAAFETSAHTVYY 308
            .| ..:...|.||:.|..:.      |.||...|    :|..:|.||..:.:....:|:|..:.:
  Rat   266 KSRKAQLQDEEELQKVKQKRRLDFLDILLFARIENGSSLSDKDLRAEVDTFMFEGHDTTASGISW 330

  Fly   309 ALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRETLE 373
            ....||..||||:....||:.  .|..|..:|..||.::.|....:.|.||:.|.|...||....
  Rat   331 IFYALATNPEHQQGCRKEIQS--LLGDGASITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLST 393

  Fly   374 DLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFSKGKRNC 438
            .:...:|..:|||:|:.:..:....|...|.:... |:|..|.||.  .||.::|:|||.|.|||
  Rat   394 PVTFPDGRSLPKGITVMLSFYGLHHNPTVWPNPEV-FDPYRFAPES--SRHSHSFLPFSGGARNC 455

  Fly   439 IGWRYGLMSSKLALVKILRNYKL---KTSFPYENLEFVDHMVIK 479
            ||.::.:...|:|:...|..::|   .|..|..    :..:|:|
  Rat   456 IGKQFAMNELKVAVALTLLRFELLPDPTRIPIP----IPRLVLK 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	110/435 (25%)
Cyp4a8	NP_113793.2	CYP4B-like	70..503	CDD:410771	111/446 (25%)