Protein Alignment Cyp313a2 and cyp-13A1

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 505
• Identity: 116/505 - (22%)
• Similarity: 210/505 - (41%)
• Gaps: 84/505 - (16%)

  Fly    11 SLILWIRFLWSRRKLYMLMMQLPGRMGLPLLG-------NSVRYLIISRGRMSSRTTYMDKHGST 68
            |..:|....|.||.:.       |.||.|:||       |:..:.:..|       .:..|.|..
 Worm    18 SYYIWQWTFWRRRGVV-------GPMGFPVLGVFLNSLDNNFPFPLQCR-------EWTKKFGKI 68

  Fly    69 YMAWIGTTPIVITRDPKIAEKVLTSPF------------CINRSSQTTNALALSMGYGLLTLQGS 121
            |....||...::..||::..:|..:.:            ..:...:.||         |...||.
 Worm    69 YGFTEGTLKTLVISDPELVHEVFVTQYDNFYGRKRNPIQGDSEKEKRTN---------LFAAQGF 124

  Fly   122 KWMARRKHMNPAFKHSVLLS-FLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTTL 185
            :|...|...:|.|.:|.|.. :..:.::..:||..:.....|..:.|:|.....::..:..:..:
 Worm   125 RWKRLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSAGGKQIDMLKFYQEFTLDVIGRIAM 189

  Fly   186 GTDVTKDDNFEN---DAILKTYQ-SMLRLTIINIFVPFVQNKIVSKLFGLEWLRRRDASAINKMI 246
            |.  |....|:|   ..:.|.:| :..:|.:|....|....:|:.::. |:.|:......||::.
 Worm   190 GQ--TDSQMFKNPIMPIVSKLFQGNFAKLFLIGGIFPTFLVEIIRQIL-LKNLKVGSFRKINEIT 251

  Fly   247 NNILDKKLNSNPEN----------------YCESELKTVIH--------RAIELFRNDEMSLMEL 287
            .:.:..::....|:                :.:::.:.|.|        .....:.|.:::..|:
 Worm   252 LDAIHNRIKQREEDQKNGIEIGEPADFIDLFLDAKAEDVEHFGENNGDFSKSTTYTNRQLTTEEI 316

  Fly   288 GAECSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDR 352
            ..:|:..::|.|:|:|.::.||..|||..||.|:.:..|:....|   ..|||...|.:|.|::.
 Worm   317 VGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKKLQEEVNRECP---NPEVTIDQLSKLKYMEC 378

  Fly   353 VLNETLRLMPSVPF-SSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFL 416
            |..|.|||.|...| :||..:.:.:|.| :.:..|..|.:|.:....:.:.||.:|..|.||.:.
 Worm   379 VFKEALRLYPLGAFANSRRCMRNTKLGN-MKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQ 442

  Fly   417 ---PEKIHDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKT 463
               .::|:.:..|  |||..|.|.|||.|...|..|:.||.|||.:..:|
 Worm   443 TPNSDQIYQKSGY--IPFGLGPRQCIGMRLAYMEEKILLVHILRKFTFET 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	102/443 (23%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	103/445 (23%)