Protein Alignment Cyp313a2 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 529
• Identity: 144/529 - (27%)
• Similarity: 235/529 - (44%)
• Gaps: 92/529 - (17%)

  Fly     6 LLIAASLILWIRFLWSRRKLYML---------MMQLPGRMGLPLLGNSVRYLIISRGRMSSRTTY 61
            ||:..||:|          ||:.         .:.:||...||.||..:.|   .:|........
  Rat    13 LLLVISLVL----------LYLYGTHSHGIFKKLGIPGPKPLPFLGTILAY---RKGFWEFDKYC 64

  Fly    62 MDKHGSTYMAWIGTTPIVITRDPKIAEKVLT----SPFCINRSSQTTNAL--ALSMGYGLLTLQG 120
            ..|:|..:..:.|..|::...||.|.:.||.    |.|...|:......|  |:|:.      :.
  Rat    65 HKKYGKLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVGILKKAISIS------ED 123

  Fly   121 SKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLI-RWSFAIATQTT 184
            .:|...|..::|.|....|....||.|..||:||........:|:...:.|:. .:|..:.|.|:
  Rat   124 EEWKRIRALLSPTFTSGKLKEMFPIINQYTDMLVRNMRQGSEEGKPTSMKDIFGAYSMDVITATS 188

  Fly   185 LGTDVTKDDNFEN--DAILKTYQSMLRLTIIN-IFVPFVQNKIVSKLFGLEWLR----RRDA--- 239
            .|.:|   |:..|  |..::..:.:|:..|.: :|:.......::.||  |.|.    .||.
  Rat   189 FGVNV---DSLNNPQDPFVEKIKKLLKFDIFDPLFLSVTLFPFLTPLF--EALNVSMFPRDVIDF 248

  Fly   240 --SAINKMINNILDKK---------LNSNPENYCESELKTVIHRAIELFRNDEMSLMELGAECSS 293
              :::.:|..|.:.:|         |..|.:|   |::|. .|:|        :|.:|:.|:...
  Rat   249 FKTSVERMKENRMKEKEKQRMDFLQLMINSQN---SKVKD-SHKA--------LSDVEIVAQSVI 301

  Fly   294 MVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETL 358
            .:.|.:||::..:.:.|.|||:.|:.|:.:.:||....|  .....|:..|.|:.|||.|:||||
  Rat   302 FIFAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALP--NKAHATYDTLLQMEYLDMVVNETL 364

  Fly   359 RLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDR 423
            ||.|......|....|:.: |||.||||..:.|..|...::..|| .|..:|.||.|..:...:.
  Rat   365 RLYPIAGRLERVCKTDVEI-NGVFIPKGTVVMIPTFALHKDPHYW-PEPEEFRPERFSKKNQDNI 427

  Fly   424 HPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKL----KTSFPYENLEFVDHMVIKLAQSP 484
            :||.::||..|.|||||.|:.||:.|:|||::|:|:..    :|..|           :||::..
  Rat   428 NPYMYLPFGNGPRNCIGMRFALMNMKVALVRVLQNFSFQPCKETQIP-----------LKLSKQG 481

  Fly   485 QLAFERRTL 493
            .|..|:..|
  Rat   482 LLQPEKPLL 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	125/452 (28%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	129/462 (28%)