DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a2 and Cyp4f13

DIOPT Version :9

Sequence 1:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster
Sequence 2:	NP_570952.1	Gene:	Cyp4f13 / 170716	MGIID:	2158641	Length:	523	Species:	Mus musculus

Alignment Length:	478	Identity:	123/478 - (25%)
Similarity:	201/478 - (42%)	Gaps:	41/478 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IAASLILWIRFLWSRRKLYMLMMQLP------GRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHG 66
            |.|.::.||...:..........|.|      |.:.|..........|...|.        |.|
Mouse    30 ILARILAWIYAFYDNCSRLRCFPQPPKPSWFWGHLALMKNNEESMQFITHLGH--------DFH- 85

  Fly    67 STYMAWIGTT-PIVITRDPKIAEKVLTSPFCINRSSQTT-NALALSMGYGLLTLQGSKWMARRKH 129
            ..:::|:|.. ||:....|.....:|.:...:.....|. ..|...:|.|||...|.||...|:.
Mouse    86 DVHLSWVGPVYPILRLVHPNFIAPLLQASAAVAPKEMTLYGFLKPWLGDGLLMSAGDKWSHHRRL 150

  Fly   130 MNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTTLGTDVTKDDN 194
            :.|||...:|.|::.|||...:::.:.:.....:|...:  |:.. ..::.|..:|...:...|:
Mouse   151 LTPAFHFDILKSYVKIFNKSVNIMHAKWQCLASKGTSRL--DMFE-HISLMTLDSLQKCIFSVDS 212

  Fly   195 FENDAILKTYQSMLRLTIINI---FVPFVQNKIVSKLFGLEWLRRRDASAINKMINNILD----- 251
            ...::..|...::|.|:.:.:   ..||:   .:..|:.|....||...|.: :::|..|
Mouse   213 NCQESDSKYIAAILELSSLVVKRHRQPFL---YLDLLYYLTADGRRFRKACD-LVHNFTDAVIKE 273

  Fly   252 --KKLNSNPENYCESELKTVIHRAIE--LFRNDE----MSLMELGAECSSMVLAAFETSAHTVYY 308
              ..||:....:.:::.||.....|:  |...||    :|..::.||..:.:....:|:...:.:
Mouse   274 RRSTLNTQGVEFLKAKAKTKTLDFIDVLLMAEDEHGKGLSNEDIRAEADTFMFGGHDTTTSALSW 338

  Fly   309 ALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRETLE 373
            .|..||..||:||....|::|........|:...||.||.:|...:.|:|||.|.|...||...:
Mouse   339 ILYNLARHPEYQERCRQEVQELLRDRDSEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCTQ 403

  Fly   374 DLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFSKGKRNC 438
            |:.|.:|..||||....|.||....|...| .:...:||..|.||....|.|.||||||.|.|||
Mouse   404 DVLLPDGRAIPKGNICVISIFGVHHNPSVW-PDPEVYNPFRFDPENPQKRSPLAFIPFSAGTRNC 467

  Fly   439 IGWRYGLMSSKLALVKILRNYKL 461
            ||..:.:...|:||...|..:::
Mouse   468 IGQTFAMSEIKVALALTLLRFRI 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	118/453 (26%)
Cyp4f13	NP_570952.1	p450	52..513	CDD:278495	119/456 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810