Protein Alignment Cyp313a2 and CYP26A1

DIOPT Version :9

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_000774.2
• Gene: CYP26A1 / 1592
• HGNCID: 2603
• Length: 497
• Species: Homo sapiens
• Alignment Length: 504
• Identity: 123/504 - (24%)
• Similarity: 211/504 - (41%)
• Gaps: 75/504 - (14%)

  Fly     6 LLIAASLILWIRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRG--RMSSRTTYMDKHGST 68
            ||..|::.||..:..|.|.....:...||.||.|..|.:::.::..|.  :|..|     |:|..
Human    19 LLFLAAIKLWDLYCVSGRDRSCALPLPPGTMGFPFFGETLQMVLQRRKFLQMKRR-----KYGFI 78

  Fly    69 YMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLT-LQGSKWMARRKHMNP 132
            |...:...|.|.........::|.....: .|.....::...:|.|.|: |..|....|:|.:..
Human    79 YKTHLFGRPTVRVMGADNVRRILLGEHRL-VSVHWPASVRTILGSGCLSNLHDSSHKQRKKVIMR 142

  Fly   133 AFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVL--SDLIRWSFAIATQTTLGTD--VTKDD 193
            ||....|..::|:...|..   |..:.::..||:.:|  .::.|..|.||.:..||.:  :..|.
Human   143 AFSREALECYVPVITEEVG---SSLEQWLSCGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDG 204

  Fly   194 NFENDAILKTYQSMLR-LTIINIFVPF----------------VQNKIVSKLFGLEWLRRRDASA 241
            :.|.. :::.::.|.| |..:.|.|||                ::..|.:|:.|   ||..:|.
Human   205 DSEQQ-LVEAFEEMTRNLFSLPIDVPFSGLYRGMKARNLIHARIEQNIRAKICG---LRASEAG- 264

  Fly   242 INKMINNILDKKLNSNPENYCESELKTVIHRAIELFRNDEMSLMELGAECSSMVLAAFETSAHTV 306
                              ..|:..|:.:|..:.|  |.:.:.:..|....:.::....||:|...
Human   265 ------------------QGCKDALQLLIEHSWE--RGERLDMQALKQSSTELLFGGHETTASAA 309

  Fly   307 YYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTD---LQQLVYLDRVLNETLRLMPSVPFSS 368
            ...:..|.::|...:.|..|:|....|.|..:....|   |:||.|:..|:.|||||.|.||...
Human   310 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGF 374

  Fly   369 RETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFSK 433
            |..|:...| ||..||||..:...|.:|....:.: :...:|||:.|:.....|...::||||..
Human   375 RVALKTFEL-NGYQIPKGWNVIYSICDTHDVAEIF-TNKEEFNPDRFMLPHPEDASRFSFIPFGG 437

  Fly   434 GKRNCIGWRYGLMSSKLALVKILRNY---------KLKTS---FPYENL 470
            |.|:|:|..:..:..|:..|::.|:.         .:|||   :|.:||
Human   438 GLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	110/465 (24%)
CYP26A1	NP_000774.2	p450	14..492	CDD:299894	123/504 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4598
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860