Protein Alignment Cyp313a2 and CYP4B1

DIOPT Version :9

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Alignment Length: 524
• Identity: 116/524 - (22%)
• Similarity: 213/524 - (40%)
• Gaps: 85/524 - (16%)

  Fly     6 LLIAASLILWIRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGSTYM 70
            |::....:..|..|..|:.|...|.:.||.....|.|:::.  |...|.:....::..:....:.
Human    20 LILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALE--IQETGSLDKVVSWAHQFPYAHP 82

  Fly    71 AWIGT-TPIVITRDPKIAEKVLT--SPFCINRSSQTTNALALSMGYGLLTLQGSKWMARRKHMNP 132
            .|.|. ...:...:|..|:.|.:  .|    ::....:.....:|.|||.|:|.||:..||.:.|
Human    83 LWFGQFIGFLNIYEPDYAKAVYSRGDP----KAPDVYDFFLQWIGRGLLVLEGPKWLQHRKLLTP 143

  Fly   133 AFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEK-DVLSDLIRWSFAIATQTTLGTDVT-----K 191
            .|.:.||..::.:|...|.:::..::....:|:. |:..|:...:.....:.|.|...|     :
Human   144 GFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSR 208

  Fly   192 DDNFENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFG---LEWL------------------- 234
            |.::        |.::..||::      :|.::||..:.   :.||
Human   209 DSSY--------YLAVSDLTLL------MQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTD 259

  Fly   235 ---RRRDASAINKMINNILDKKLNSNPENYCESELKTVIHRAIELFRNDE----MSLMELGAECS 292
               |.|.|:        :.|:|:....:|....:...::     |...||    :|..:|.||..
Human   260 QVIRERKAA--------LQDEKVRKKIQNRRHLDFLDIL-----LGARDEDDIKLSDADLRAEVD 311

  Fly   293 SMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNET 357
            :.:....:|:...:.:.|..:|::||||.....|::|  .|.........||.::.||...:.|:
Human   312 TFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVRE--ILGDQDFFQWDDLGKMTYLTMCIKES 374

  Fly   358 LRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHD 422
            .||.|.||...|:..:.:...:|..:|.|..||:.|:...||:..| .:...|:...|..|....
Human   375 FRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVW-PDPEVFDSLRFSTENASK 438

  Fly   423 RHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQLA 487
            |||:||:|||.|.|||||.::.:...|:.....|..::....        ...:.||:   |||.
Human   439 RHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLD--------PSRLPIKM---PQLV 492

  Fly   488 FERR 491
            ...:
Human   493 LRSK 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	105/467 (22%)
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	110/497 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810