Protein Alignment Cyp313a2 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 481
• Identity: 114/481 - (23%)
• Similarity: 215/481 - (44%)
• Gaps: 51/481 - (10%)

  Fly     6 LLIAASLILWIRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGSTYM 70
            :::..:::..:..|:.|:||...:...||.....|.|:::.  |...|.:....|:.::....:.
Mouse    20 VILMVTVLKLLSLLFRRQKLARALDSFPGPPKHWLFGHALE--IQKTGGLDKVVTWTEQFPYAHP 82

  Fly    71 AWIGTTPIVIT-RDPKIAEKVLT--SPFCINRSSQTTNALALSMGYGLLTLQGSKWMARRKHMNP 132
            .|:|...:.:. .:|..|:.|.:  .|    :::...:.....:|.|||.|:|.||...||.:.|
Mouse    83 LWLGQFIVFLNIYEPDYAKAVYSRGDP----KAAYVYDFFLQWIGKGLLVLEGPKWFQHRKLLTP 143

  Fly   133 AFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEK-DVLSDLIRWSFAIATQTTLG---TDVTKDD 193
            .|.:.||..::.||...|.:::..::....:.:. |:..|:...:.....:.|.|   :.::..|
Mouse   144 GFHYDVLKPYVAIFAESTRVMLDKWEKKASENKSFDIFCDVGHMALDTLMKCTFGKGDSGLSHSD 208

  Fly   194 NFENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFG---LEWL----RR--RDASAINKMINNI 249
            |       ..|.::..||::      :|.:|.|..:.   :.||    ||  |.....:...:::
Mouse   209 N-------SYYLAVSDLTLL------MQQRIDSFQYHNDFIYWLTPHGRRFLRACQIAHDHTDHV 260

  Fly   250 LDKKLNSNPENYCESELKTVIHRA------IELFRNDE----MSLMELGAECSSMVLAAFETSAH 304
            :.::..:..:   |.|.|.:..|.      |.|...||    :|..:|.||..:.:....:|:..
Mouse   261 IRQRKAALQD---EKEQKKLQERRHLDFLDILLGARDESGIKLSDADLRAEVDTFMFEGHDTTTS 322

  Fly   305 TVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSR 369
            .:.:.|..:|::|.||:....|::|  .|.........||.|:.||...:.|..||.|.||...|
Mouse   323 GISWFLYCMALYPMHQQRCREEVRE--ILGDRDSFQWDDLAQMTYLTMCMKECFRLYPPVPQVYR 385

  Fly   370 ETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFSKG 434
            :..:.:...:|..:|.|..||:.|:...||:..| .:...|:|..|.||.:..|||:||:|||.|
Mouse   386 QLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVW-PDPEVFDPLRFSPENMTGRHPFAFMPFSAG 449

  Fly   435 KRNCIGWRYGLMSSKLALVKILRNYK 460
            .|||||.::.:...|:.....|..::
Mouse   450 PRNCIGQQFAMNEMKVVTALCLLRFE 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	103/421 (24%)
Cyp4b1	NP_031849.1	CYP4B-like	67..501	CDD:410771	104/432 (24%)