Protein Alignment Cyp313a2 and Cyp4a14

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 539
• Identity: 126/539 - (23%)
• Similarity: 211/539 - (39%)
• Gaps: 112/539 - (20%)

  Fly     7 LIAASLILW--IRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGSTY 69
            |::..|:|:  ::|...|:.|...:...|......|.|:.::                ||.....
Mouse    24 LLSLFLVLFKAVQFYLRRQWLLKTLQHFPCMPSHWLWGHHLK----------------DKELQQI 72

  Fly    70 MAWI------------GTTPIVITRDPKIAEKVL--TSPFCINRSSQTTNALALSMGYGLLTLQG 120
            :.|:            |:...|:..||...:.||  :.|    ::|......|..:|||||.|.|
Mouse    73 LIWVEKFPSACLQCLSGSNIRVLLYDPDYVKVVLGRSDP----KASGIYQFFAPWIGYGLLLLNG 133

  Fly   121 SKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTTL 185
            .||...|:.:.|||.:.:|..::.|.....::::..::...||.....:       |...:..||
Mouse   134 KKWFQHRRMLTPAFHYDILKPYVKIMADSVNIMLDKWEKLDGQDHPLEI-------FHCVSLMTL 191

  Fly   186 GTDVTKDDNFENDAILK---TYQSMLRLTIINIFVPFVQN-----KIVSKLFGLEWLRRRDA-SA 241
                        |.::|   :||..::|.         :|     |.|..|..|.:.|.|:| ..
Mouse   192 ------------DTVMKCAFSYQGSVQLD---------ENSKLYTKAVEDLNNLTFFRLRNAFYK 235

  Fly   242 INKMINNILDKKLNSNPENYCESELKTVIHRAIELFRNDE------------------------- 281
            .|.:.|...|.:|:.:...........||.......:|:|
Mouse   236 YNIIYNMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQNEEELQKARKKRHLDFLDILLFARMEDR 300

  Fly   282 --MSLMELGAECSSMVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDL 344
              :|..:|.||..:.:....:|:|..:.:....||..||||:....|::.  .|..|..||...|
Mouse   301 NSLSDEDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQQRCREEVQS--ILGDGTSVTWDHL 363

  Fly   345 QQLVYLDRVLNETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQ 409
            .|:.|....:.|.|||.|.|...|||....:...:|..||||:|.:|.|:....|..:|.:...
Mouse   364 GQMPYTTMCIKEALRLYPPVISVSRELSSPVTFPDGRSIPKGITATISIYGLHHNPRFWPNPKV- 427

  Fly   410 FNPENFLPEKIHDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKL---KTSFPYENLE 471
            |:|..|.|:..|  |.:|::|||.|.|||||.::.:...|:|:...|..::|   .|..|..
Mouse   428 FDPSRFAPDSSH--HSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVP--- 487

  Fly   472 FVDHMVIKLAQSPQLAFER 490
             :..:|:|......|..::
Mouse   488 -IARLVLKSKNGIHLCLKK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	114/473 (24%)
Cyp4a14	NP_031848.1	CYP4B-like	69..502	CDD:410771	114/473 (24%)