Protein Alignment Cyp313a2 and Cyp4a12b

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 489
• Identity: 116/489 - (23%)
• Similarity: 207/489 - (42%)
• Gaps: 55/489 - (11%)

  Fly     3 VIQLLIAASLILWIRFLWSRRKLYM-------LMMQLPGRMGLPLLGNSVRYLIISRGRMSSRTT 60
            :.:.|..||::..:..|:...:||:       ...|.|......|.|:.    |:....:....|
Mouse    15 ISEYLQVASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGHK----ILKDQDLQDILT 75

  Fly    61 YMDKHGSTYMAWI-GTTPIVITRDPKIAEKVLTSPFCINRSSQTTNA----LALSMGYGLLTLQG 120
            .:....|....|: |:...:...||...:.:|      .||....:.    ||..:|.|||.|.|
Mouse    76 RIKNFPSACPQWLWGSKVRIQVYDPDYMKLIL------GRSDPKAHGSYRFLAPWIGRGLLLLDG 134

  Fly   121 SKWMARRKHMNPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTTL 185
            ..|...|:.:.|||.:.:|..:..|......:::..::..|||   |...::.:....:...|.:
Mouse   135 QTWFQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQIVGQ---DSTLEIFQHITLMTLDTIM 196

  Fly   186 GTDVTKDDNFENDAILKTY-------QSMLRLTIINIFVPFVQNKIVSKLFGLEWLRRRDASAIN 243
            ....:.:.:.:.|...|:|       .::..|.:.||   |.||.|:.::.....|    |::..
Mouse   197 KCAFSHEGSVQLDRKYKSYIQAVEDLNNLFFLRVRNI---FHQNDIIYRVSSNGCL----ANSAC 254

  Fly   244 KMINNILDKKLNS-NPENYCESELKTVIHRA------IELFRNDE----MSLMELGAECSSMVLA 297
            ::.::..|:.:.| ..:...|.||:.:..:.      |.||...|    :|..:|.||..:.:..
Mouse   255 QLAHDHTDQVIKSRRSQLQDEEELEKLKKKRRLDFLDILLFARMENGKSLSDKDLRAEVDTFMFE 319

  Fly   298 AFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMP 362
            ..:|:|..:.:....||..||||:....||:.  .|..|..:|..||.::.|....:.|.||:.|
Mouse   320 GHDTTASGISWIFYALATNPEHQQRCRKEIQS--LLGDGASITWNDLDKMPYTTMCIKEALRIYP 382

  Fly   363 SVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYA 427
            .||..|||....:...:|..:|||:.:.:..:....|...|.:... |:|..|.|..  .||.::
Mouse   383 PVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVWPNPEV-FDPSRFAPGS--SRHSHS 444

  Fly   428 FIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKL 461
            |:|||.|.|||||.::.:...|:|:...|..::|
Mouse   445 FLPFSGGARNCIGKQFAMNELKVAVALTLLRFEL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	104/419 (25%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	105/430 (24%)