Protein Alignment Cyp313a2 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 483
• Identity: 129/483 - (26%)
• Similarity: 221/483 - (45%)
• Gaps: 42/483 - (8%)

  Fly     6 LLIAASLILWIRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGSTYM 70
            :|:|.||:|..|:...:.:|:. ...:||...||.||..:.|.   :|..........|:|.|:.
Mouse    13 VLLAISLVLLYRYGTRKHELFK-KQGIPGPKPLPFLGTVLNYY---KGLWKFDMECYKKYGKTWG 73

  Fly    71 AWIGTTPIVITRDPKIAEKVLTSP-FCINRSSQTTNALALSMGYGLLTLQGSKWMARRKHMNPAF 134
            .:.|.||::...||:..:.||... |.:..:.:....:.: |...:...:..:|...|..::|.|
Mouse    74 LFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGI-MSKAISISKDDEWKRYRALLSPTF 137

  Fly   135 KHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLI-RWSFAIATQTTLGTDVTKDDNFEND 198
            ....|....|:.....|:||........:|:...:.|:: .:|..:.|.|:.|.:|...:|.| |
Mouse   138 TSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGAYSMDVITSTSFGVNVDSLNNPE-D 201

  Fly   199 AILKTYQSMLRLTIIN------IFVPFVQNKIVSKLFGLEWLRRRDASAINKMINNILDKKLNSN 257
            ..::..:.:||....:      :..||:..  |.::..:....:.......|.::.:.:.:|:|.
Mouse   202 PFVEKAKKLLRFDFFDPLLFSVVLFPFLTP--VYEMLNICMFPKDSIEFFKKFVDRMKESRLDSK 264

  Fly   258 PE----------NYCESELKTVIHRAIELFRNDEMSLMELGAECSSMVLAAFETSAHTVYYALVL 312
            .:          |...:....|.|:|        :|.||:.|:....:.|.:||::.|:.:.|..
Mouse   265 QKHRVDFLQLMMNSHNNSKDKVSHKA--------LSDMEITAQSIIFIFAGYETTSSTLSFTLHS 321

  Fly   313 LAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVPFSSRETLEDLRL 377
            ||..|:.|:.:.:||.|..|  .....|:..:.::.|||.||||||||.|......|...:|:.|
Mouse   322 LATHPDIQKKLQDEIDEALP--NKAPPTYDTVMEMEYLDMVLNETLRLYPIANRLERVCKKDVEL 384

  Fly   378 SNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIPFSKGKRNCIGWR 442
             |||.||||.|:.|..:....:..:| ||..:|.||.|..|......||.::||..|.|||:|.|
Mouse   385 -NGVYIPKGSTVMIPSYALHHDPQHW-SEPEEFQPERFSKENKGSIDPYVYLPFGNGPRNCLGMR 447

  Fly   443 YGLMSSKLALVKILRNYKL----KTSFP 466
            :.||:.||||.||::|:..    :|..|
Mouse   448 FALMNMKLALTKIMQNFSFQPCKETQIP 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	CYP313-like	66..487	CDD:410680	113/423 (27%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	114/425 (27%)