Protein Alignment Cyp313a2 and CYP4F22

DIOPT Version :9

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_775754.2
• Gene: CYP4F22 / 126410
• HGNCID: 26820
• Length: 531
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 121/521 - (23%)
• Similarity: 223/521 - (42%)
• Gaps: 94/521 - (18%)

  Fly    14 LWIRFLWSRRKLYMLMMQL-----PGRMGLPLLGNSVRYLIISRGRMSSRTTYMDKHGSTYMAWI 73
            |.:|||...|..|:...:|     |.|... |||:...||....| :......:|......:.|:
Human    38 LLLRFLRLCRSFYITCRRLRCFPQPPRRNW-LLGHLGMYLPNEAG-LQDEKKVLDNMHHVLLVWM 100

  Fly    74 G-TTPIVITRDPKIAEKVLTSPFCI-NRSSQTTNALALSMGYGLLTLQGSKWMARRKHMNPAFKH 136
            | ..|:::...|...:.:|.:...| .:.......|...:|.|||..:|.||...|:.:.|||..
Human   101 GPVLPLLVLVHPDYIKPLLGASAAIAPKDDLFYGFLKPWLGDGLLLSKGDKWSRHRRLLTPAFHF 165

  Fly   137 SVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTTLGTDVTKDDNFEN---- 197
            .:|..::.|||...|::.:                  :|.. :|..:.:..|:     ||:
Human   166 DILKPYMKIFNQSADIMHA------------------KWRH-LAEGSAVSLDM-----FEHISLM 206

  Fly   198 --DAILK---TYQS------------MLRLTIINI--------FVPFVQNKIVSKLFGLEWLRRR 237
              |::.|   :|.|            ::.|:.:::        ::.|:..:...   |..:  |:
Human   207 TLDSLQKCVFSYNSNCQEKMSDYISAIIELSALSVRRQYRLHHYLDFIYYRSAD---GRRF--RQ 266

  Fly   238 DASAINKMINNILDKKLNSNPENYCESELKTVIHRAIE------LFRND---EMSLMELGAECSS 293
            ....::.....::.::..:..:...|:.||....:.::      |.|::   |:|..::.||..:
Human   267 ACDMVHHFTTEVIQERRRALRQQGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADT 331

  Fly   294 MVLAAFETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTH---TDLQQLVYLDRVLN 355
            .:....:|::..:.:.|..||.:||:||....||:|   :.||.|:..   .||.||.:....:.
Human   332 FMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQE---VMKGRELEELEWDDLTQLPFTTMCIK 393

  Fly   356 ETLRLMPSVPFSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKI 420
            |:||..|.|...||:..||::|.:|.:||||:...:.|:.|..|...| .::..:||..|.|:..
Human   394 ESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVW-PDSKVYNPYRFDPDNP 457

  Fly   421 HDRHPYAFIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQ 485
            ..|.|.|::|||.|.|||||..:.:...::.:...|..::|.          ||. ..|:.:.|:
Human   458 QQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLS----------VDR-TRKVRRKPE 511

  Fly   486 L 486
            |
Human   512 L 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	109/472 (23%)
CYP4F22	NP_775754.2	p450	60..524	CDD:278495	114/499 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810