Protein Alignment Cyp313a2 and CYP46A1

DIOPT Version :9

• Sequence 1: NP_650169.3
• Gene: Cyp313a2 / 41487
• FlyBaseID: FBgn0038006
• Length: 493
• Species: Drosophila melanogaster
• Sequence 2: NP_006659.1
• Gene: CYP46A1 / 10858
• HGNCID: 2641
• Length: 500
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 96/422 - (22%)
• Similarity: 183/422 - (43%)
• Gaps: 78/422 - (18%)

  Fly    76 TPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQG-------SKWMARRKHMNPA 133
            |.:::|....:.:.::::.:  |:.|:...||....|..|.. ||       .:|..:|:.::.|
Human    83 TSVIVTSPESVKKFLMSTKY--NKDSKMYRALQTVFGERLFG-QGLVSECNYERWHKQRRVIDLA 144

  Fly   134 FKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDV-LSDLIRW---------SFAIATQTTLGTD 188
            |..|.|:|.:..||.:.:.||.:.:: ...|:..| :.|::.:         :|.:.|...||..
Human   145 FSRSSLVSLMETFNEKAEQLVEILEA-KADGQTPVSMQDMLTYTAMDILAKAAFGMETSMLLGAQ 208

  Fly   189 VTKDDNFENDAILKTYQSMLRLTIINI---------FVPFVQNKI--------VSKLFGLEWL-R 235
                         |.....::|.:..|         |:|..:.::        ..:..|.:|: |
Human   209 -------------KPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIRFLRQVGRDWVQR 260

  Fly   236 RRDASAINKMINNILDKKLNSNPENYCESELKTVIHRAIELFRNDEMSLMELGAECSSMVLAAFE 300
            ||:|              |....|  ..:::.|.|.:|.|..::|| .|::   ...:..:|..|
Human   261 RREA--------------LKRGEE--VPADILTQILKAEEGAQDDE-GLLD---NFVTFFIAGHE 305

  Fly   301 TSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPSVP 365
            |||:.:.:.::.|:..||....:..|:.|.....:.::  ..||.:|.||.:||.|:|||.|..
Human   306 TSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLD--FEDLGRLQYLSQVLKESLRLYPPA- 367

  Fly   366 FSSRETLEDLRLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYAFIP 430
            :.:...||:..|.:||.:|....:....:...|...|: .:...|||:.|.|.....|  :.:.|
Human   368 WGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYF-EDPLTFNPDRFGPGAPKPR--FTYFP 429

  Fly   431 FSKGKRNCIGWRYGLMSSKLALVKILRNYKLK 462
            ||.|.|:|||.::..|..|:.:.|:|:..:.:
Human   430 FSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFR 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	96/422 (23%)
CYP46A1	NP_006659.1	p450	34..466	CDD:365848	96/422 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920