Protein Alignment Cyp313a5 and CYP4F2

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_001073.3
• Gene: CYP4F2 / 8529
• HGNCID: 2645
• Length: 520
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 117/442 - (26%)
• Similarity: 189/442 - (42%)
• Gaps: 67/442 - (15%)

  Fly    54 IRLRTILFKIYGKTVLTWIG-LTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISS----CLGLG 113
            :|:.|.|...|.:....|:| ::|:|..|.|.|:..:.   |.|...:..||...|    .||.|
Human    74 MRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVI---NASAAIAPKDKFFYSFLEPWLGDG 135

  Fly   114 LLTLKNNHWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVT---LLA-------EFVDGGDINLL 168
            ||....:.|:..|::|.|:|..|.:..::.:.|...|.:..   |||       :..:...:..|
Human   136 LLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSACLDMFEHISLMTL 200

  Fly   169 PELNKWSFK------------IAAQITMGDEVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRN 221
            ..|.|..|.            |||.:    |:....:.::..:|.....|..|.|.|  ..:.|.
Human   201 DSLQKCVFSFDSHCQEKPSEYIAAIL----ELSALVSKRHHEILLHIDFLYYLTPDG--QRFRRA 259

  Fly   222 KYLGKLFS----YEKRR----------LEAATQSNAFIKDIIDKKLSSTDNSSEPALIDRILNLV 272
            ..|...|:    .|:||          |:|..:|...  |.||..|.|.|...:
Human   260 CRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTL--DFIDVLLLSKDEDGK----------- 311

  Fly   273 RIGELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHA 337
               :||.:|:..|....:|...||.:..::.||..:|..|:||:...:|:.|:.......|....
Human   312 ---KLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWD 373

  Fly   338 DLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQA 402
            ||..|..|...:.|::||.|.||::.|..:..|.|.:|..||:|:..:|.:|.||.|..:| |..
Human   374 DLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVW-PDP 437

  Fly   403 NAFNPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNY 454
            ..::|..|.|||.:.|.|.:::|||.|.:.|:|...::...|:.||..|..:
Human   438 EVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRF 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	113/431 (26%)
CYP4F2	NP_001073.3	CYP4F	74..515	CDD:410772	117/442 (26%)