Protein Alignment Cyp313a5 and CYP4F12

DIOPT Version :9

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_076433.3
• Gene: CYP4F12 / 66002
• HGNCID: 18857
• Length: 524
• Species: Homo sapiens
• Alignment Length: 460
• Identity: 112/460 - (24%)
• Similarity: 183/460 - (39%)
• Gaps: 98/460 - (21%)

  Fly    64 YGKTVLTWIG-LTPVLVTCEPKILEDIF-TSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERR 126
            |.:....|:| :.|.:|.|.|..:..|. .|...:.:.::..:.:...||.|:|....:.|:..|
Human    84 YSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHR 148

  Fly   127 KLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINL----------LPELNKWSFK---- 177
            ::|.|:|..|.:.|::.:.|..||.::.........|...|          |..|.|..|.
Human   149 RMLTPAFHFNILKSYITIFNKSANIMLDKWQHLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSH 213

  Fly   178 --------IAAQITMGD--EVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYL---GKLFS 229
                    ||..:.:..  |.|:|...|:.:.|                     .||   |:.|.
Human   214 CQERPSEYIATILELSALVEKRSQHILQHMDFL---------------------YYLSHDGRRFH 257

  Fly   230 -------------YEKRRLEAATQS-NAFIK--------DIIDKKLSSTDNSSEPALIDRILNLV 272
                         ..:||....||. :.|.|        |.||..|.|.|...:
Human   258 RACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGK----------- 311

  Fly   273 RIGELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHA 337
               .||.:|:..|....:|...||.:..::.||..:|..|:||:...:|:.|:.......|....
Human   312 ---ALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWD 373

  Fly   338 DLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQA 402
            ||.:|..|...:.|::||.|..|.:.|..:..|.|.:|..||:|:|.:|||...|.|..:| |..
Human   374 DLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVW-PDP 437

  Fly   403 NAFNPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYMLSTTFLYKDLRF 467
            ..::|..|.|||.:.|.|.:::|||.|.:.|:|...::...|:.||.:|.::           ||
Human   438 EVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHF-----------RF 491

  Fly   468 IDNTT 472
            :.:.|
Human   492 LPDHT 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	109/444 (25%)
CYP4F12	NP_076433.3	p450	52..506	CDD:306555	112/460 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810