Protein Alignment Cyp313a5 and cyp46a1

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_001027519.1
• Gene: cyp46a1 / 613111
• XenbaseID: XB-GENE-22069537
• Length: 507
• Species: Xenopus tropicalis
• Alignment Length: 481
• Identity: 118/481 - (24%)
• Similarity: 216/481 - (44%)
• Gaps: 61/481 - (12%)

  Fly     2 LTLQIFEAFAIILCVYFLWSRRRFYIMMLKLPGPM--GFPFIGLAFEYIRLKRKIRLRTILFKIY 64
            |||..|    ::.|.|..:...::.    .:|||.  ||.| |.:...:||.:..::      :|
 Frog    17 LTLICF----LLFCGYIQYIHMKYD----HIPGPPRDGFIF-GHSPTILRLMKNNKV------VY 66

  Fly    65 GKTVLTWI----------GLTPVLV-TCEPKILEDIFTSPNCSNRSSVVDKAIS----SCLGLGL 114
            .: .|.|:          .|..|:| ...|:.:::...||..| ::.:.|:..:    ..:|.||
 Frog    67 DQ-YLDWVQKYGPVVRINALHRVIVLITSPEGVKEFLMSPKYS-KNDIYDRVATLYGMRFMGKGL 129

  Fly   115 LTLK-NNHWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDG-GDINLLPELNKWSFK 177
            :|.| ::||.::|:::.|:|....::..:...|.:|..|:..|:|..|| .|..:....::.:..
 Frog   130 VTDKDHDHWYKQRRIMDPAFSRTYLMDLMGPFNEKAEELMERLSEQADGKSDTEMHNLFSRVTLD 194

  Fly   178 IAAQITMGDEVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSN 242
            :.|::..|.|:    |....:|....:|: :|:..|:|.  .||..:  .:|..||......|.:
 Frog   195 VIAKVAFGMEL----NSLKDDLTPLPQAI-SLVMNGIVE--TRNPMI--KYSLAKRGFIRKVQES 250

  Fly   243 AFI-----KDIIDKKLSSTDNSSEPALIDRILNLVRIGELSYD----DVMGEFSNIIFAASDTLS 298
            ..:     |:.|:::.....:..|..: |.:..:::...|..|    .::..|.....|..:|.:
 Frog   251 IRLLRQTGKECIERRQKQIQDGEEIPM-DILTQILKGAALEEDCDPETLLDNFVTFFIAGQETTA 314

  Fly   299 ITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLI 363
            ..::..::.:...|:......:|:.||..|....|  |.||.||..|.:||.||:||.|..|...
 Frog   315 NQLSFAVMELGRNPEILQKAQKEIDEVIGSRRFIE--HEDLSKLHYLSQVLKETLRLYPTAPGTS 377

  Fly   364 RQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFSK 428
            |.....|.: .|..||..|.:|.:.:...|.:..: .....||||.|.|  ...:|.|:|.|||.
 Frog   378 RGLKEEIVI-EGVRIPPNVNVMFNSYIMGRMEQNY-TDPLTFNPDRFSP--GAPKPYYTYFPFSL 438

  Fly   429 GKKTCLGWKLSLISAKLALAKILRNY 454
            |.::|:|...|.:.||:.:||:|:.|
 Frog   439 GPRSCIGQVFSQMEAKVVMAKLLQRY 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	102/416 (25%)
cyp46a1	NP_001027519.1	CYP46A1-like	66..490	CDD:410706	103/417 (25%)