Protein Alignment Cyp313a5 and Cyp3a25

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_062766.2
• Gene: Cyp3a25 / 56388
• MGIID: 1930638
• Length: 503
• Species: Mus musculus
• Alignment Length: 510
• Identity: 122/510 - (23%)
• Similarity: 220/510 - (43%)
• Gaps: 74/510 - (14%)

  Fly    12 IILCVYFLWSRRRFYIMMLKLPGPMGFPFIGLAFEYIRLKRKIRLRTILFKIYGKTVLTWIGLTP 76
            ::..:|..:|...|  ..|.:|||...|.:|..|.|  .....:.....:|.|||....:.|..|
Mouse    20 VLFYIYGTYSHGLF--KKLGIPGPKPLPLLGTIFNY--YDGMWKFDEDCYKKYGKIWGFYEGPQP 80

  Fly    77 VLVTCEPKILE--------DIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRKLLLPSF 133
            :|...:|:|::        .:||:.........:.|||:        ..::..|...|.||.|:|
Mouse    81 ILAIMDPEIIKIVLVKECYSVFTNRRFFGPVGFMKKAIT--------ISEDEEWKRLRTLLSPTF 137

  Fly   134 KNNAVLSFVPVLNNEANFLV-TLLAEFVDGGDINLLPELNKWSFKIAAQITMG---DEVRNQAN- 193
            .:..:....|::....:.|| .|..|...|..|::......:|..:....:.|   |.:.|..:
Mouse   138 TSGKLKEMFPIMRQYGDILVRNLRREEEKGEPISMKDIFGAYSMDVITGTSFGVNVDSLNNPQDP 202

  Fly   194 -YQNGNLLESYKALNNLIPIGVVMPWLRNKYLGKLFS------------YEKRRLEAATQSNAFI 245
             .|....:..:|..:..:...::.|:|...|....||            :.||..:....||.
Mouse   203 FVQKAKKILKFKIFDPFLLSIILFPFLTPIYEMLNFSIFPRDSMNFFKKFVKRMKKERLASNQ-- 265

  Fly   246 KDIID--KKLSSTDNS----SEPALIDRILNLVRIGELSYDDVMGEFSNIIFAASDTLSITVNNV 304
            |:.:|  :.:.:|.||    |:.||.|.        |::...|:     .||...|..|.:::.:
Mouse   266 KNRVDFLQLMMNTQNSKGQESQKALSDL--------EMAAQAVI-----FIFGGYDATSTSISLI 317

  Fly   305 LILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHS 369
            :..:|..|..|..:.:|:....|:  :...::..|..:..||.|::|::||.|....|.|.:...
Mouse   318 MYELATHPDVQKKLQDEIDRTLPN--KAPVTYDALMDMEYLDMVVNESLRLYPIAIRLERVSKKD 380

  Fly   370 IQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGKKTCL 434
            ::: ||.:||:|..:||.|:..|||.:.| |:...|.|:.|..|||....||.|:||..|.:.|:
Mouse   381 VEI-NGVFIPKGTVVMIPIYPLHRNPEYW-PEPQEFCPERFSKENKGNIDPYIYMPFGNGPRNCI 443

  Fly   435 GWKLSLISAKLALAKILRNYMLSTTFLYKDLRFIDNT--TMKLAEQPLLAVKRRI 487
            |.:.:|||.|||:..:|:|:.:..         .:.|  .:|::.:|:...::.|
Mouse   444 GMRFALISIKLAVIGVLQNFTVQP---------CEETQIPLKISREPIFQPEKPI 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	108/450 (24%)
Cyp3a25	NP_062766.2	CYP3A	67..492	CDD:410743	110/459 (24%)