DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a5 and Cyp4f1

DIOPT Version :9

Sequence 1:	NP_650168.1	Gene:	Cyp313a5 / 41486	FlyBaseID:	FBgn0038005	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_062569.2	Gene:	Cyp4f1 / 56266	RGDID:	70926	Length:	524	Species:	Rattus norvegicus

Alignment Length:	440	Identity:	117/440 - (26%)
Similarity:	184/440 - (41%)	Gaps:	67/440 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 TILFKIYGKTVLTWIG-LTPVLVTCEPKILEDIFTSPNCSNRSSVVD----KAISSCLGLGLLTL 117
            |.|...|.:..|.||| :.||:..|...|:..|.   |.|...::.|    ..:...||.|||..
  Rat    78 TRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSIL---NASAAVALKDVIFYTILKPWLGDGLLVS 139

  Fly   118 KNNHWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINL----------LPELN 172
            ..:.|:..|::|.|:|..|.:..:|.:.|:..|.:.......:..|...|          |..|.
  Rat   140 AGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISEGSSRLDMFEHVSLMTLDSLQ 204

  Fly   173 KWSFK------------IAAQITMGDEVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYLG 225
            |..|.            |||.:.:...|..:  :|...|.  ...|.||.|.|:..    :|...
  Rat   205 KCVFSFDSNCQEKSSEYIAAILELSALVAKR--HQQPLLF--MDLLYNLTPDGMRF----HKACN 261

  Fly   226 KLFSY------EKRR------LEAATQSNAFIK--DIIDKKLSSTDNSSEPALIDRILNLVRIGE 276
            .:..:      |:||      |:...:|.|..|  |.||..|.:.|...:              |
  Rat   262 LVHEFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTKDEDGK--------------E 312

  Fly   277 LSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEK 341
            ||.:|:..|....:|...||.:..::.:|..:|..|:||:...:|:.|:.......|....||.:
  Rat   313 LSDEDIRAEADTFMFEGHDTTASGLSWILYNLAKHPEYQERCRQEVQELLRDRDPEEIEWDDLAQ 377

  Fly   342 LVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFN 406
            |..|...:.|::||.|.|.::.|..:..|.|.:|..||:|:..:|.||..|.|..:| |....:|
  Rat   378 LPFLTMCIKESLRLHPPVTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVW-PDPEVYN 441

  Fly   407 PDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYML 456
            |..|.|||.:...|.:::|||.|.:.|:|...::...|:|||..|..:.|
  Rat   442 PFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRL 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	117/440 (27%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	117/440 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810