DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a5 and Cyp313a1

DIOPT Version :9

Sequence 1:	NP_650168.1	Gene:	Cyp313a5 / 41486	FlyBaseID:	FBgn0038005	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_650368.1	Gene:	Cyp313a1 / 41759	FlyBaseID:	FBgn0038236	Length:	492	Species:	Drosophila melanogaster

Alignment Length:	491	Identity:	225/491 - (45%)
Similarity:	342/491 - (69%)	Gaps:	5/491 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLTLQIFEAFAIILCVYFLWSRRRFYIMMLKLPGPMGFPFIGLAFE-YIRLKRKIRLRTILFKIY 64
            |||:.:..|...:..:||||||||.|.:|||:|||:|.|.:|.:.| .|..|||:..||.....|
  Fly     1 MLTINLLLAVGALFWIYFLWSRRRLYFLMLKIPGPIGLPILGSSLENIITYKRKLSFRTKYLNKY 65

  Fly    65 GKTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRKLL 129
            |.|:|||:|..|.:||.:||::||||:||:|.|:|..:..||:||:|.|||..::.||.:|||..
  Fly    66 GSTILTWMGPVPFIVTRDPKVVEDIFSSPDCHNKSQHIVNAITSCMGNGLLGKQDPHWLDRRKHF 130

  Fly   130 LPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWSFKIAAQITMGDEVRNQANY 194
            .||||.:.:|||..:.:.|...|:.||..:||.|:|:::||:.:||||||||.|||.||::..::
  Fly   131 NPSFKQDLLLSFFHIFDAETKVLMNLLDTYVDKGEIDVVPEMLRWSFKIAAQTTMGSEVKHDEHF 195

  Fly   195 QNGNLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNAFIKDIIDKK---LSST 256
            :||:|:||:::|.:...:.::||.::|:.:.|:..|:|.|.:..::....:.::::||   |..|
  Fly   196 KNGSLVESFESLISHSTLNILMPLVQNRMISKICGYDKLRADNFSRIQKMLDNVVNKKVNPLPKT 260

  Fly   257 DNSSEP-ALIDRILNLVRIGELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFE 320
            |:..|. .:|:|.:.|.|.|:::|.||..|...:|.|..||.::||.:.|.|:|..|::|:.|||
  Fly   261 DSDPESNIVINRAMELYRKGDITYMDVKSECCIMIAAGYDTSALTVYHALFLLANHPEHQEAVFE 325

  Fly   321 ELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLM 385
            ||..|||..|.|..::.|::||..|:||:.||:|||||:|:..|:|.:.::||||..||:||.:.
  Fly   326 ELNGVFPDAGHFGITYPDMQKLDYLERVIKETLRLIPAIPITARETKNDVRLSNGVLIPKGVVIG 390

  Fly   386 IDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKI 450
            ||:||||||.::|||.|:.|||||||.||...:.||:|:||::||:.|:|.|.:::|:|.||.:|
  Fly   391 IDMFHTHRNPEVWGPDADNFNPDNFLAENMEQKHPYAYIPFARGKRNCIGSKYAMMSSKFALCRI 455

  Fly   451 LRNYMLSTTFLYKDLRFIDNTTMKLAEQPLLAVKRR 486
            ||||.:||:.|||||.::||.||||||.|.|.::||
  Fly   456 LRNYKISTSTLYKDLVYVDNMTMKLAEYPRLKLQRR 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	190/429 (44%)
Cyp313a1	NP_650368.1	p450	33..463	CDD:299894	190/429 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450071
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D28972at7147
OrthoFinder	1	1.000	-	-		FOG0008559
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900