DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a5 and Cyp313a4

DIOPT Version :9

Sequence 1:	NP_650168.1	Gene:	Cyp313a5 / 41486	FlyBaseID:	FBgn0038005	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_650224.3	Gene:	Cyp313a4 / 41563	FlyBaseID:	FBgn0038076	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	494	Identity:	193/494 - (39%)
Similarity:	323/494 - (65%)	Gaps:	9/494 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLTLQIFEAFAIILCVYFLWSRRRFYIMMLKLPGPMGFPFIGLAFEYIRLKRKIRLRTILFKIYG 65
            |||..::.....:|.:||||||||||::.||:|||:|:|.:|:|...:|.:..:.........:|
  Fly     1 MLTWTLWCGLLFLLWIYFLWSRRRFYLLTLKIPGPLGYPILGMAHWLMRREDILNAFGCFLDKHG 65

  Fly    66 KTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRKLLL 130
            .|:.:|:|..|.::..:|::::||||||:|.|: .::.||:....|:||.:||:..|:..||||.
  Fly    66 PTIFSWLGPIPFMIVSDPQVVQDIFTSPHCVNK-GIIYKAVDDGAGVGLFSLKDPRWSIHRKLLN 129

  Fly   131 PSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWSFKIAAQITMGDEVRNQANYQ 195
            |:|.:..:|||:|:.|.|...|:..|....|.|:.:|:|.|..::..||.|.|||.:|:::.:::
  Fly   130 PAFGHKVLLSFLPIFNRETALLLDQLEPLQDDGEKDLIPLLQSFTLGIATQTTMGSDVKDEESFR 194

  Fly   196 NGNLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNAFIKDIIDKKLSSTDNSS 260
            :.:||..|:.:...:......|||.:::..:|...|....:|.|:...||:.||::||:..:..:
  Fly   195 SNSLLGRYQCILETMTDMCFSPWLNSRFCRQLAGKESHYYQAKTEIRQFIRKIIERKLAEDEMGA 259

  Fly   261 EPAL--------IDRILNLVRIGELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDN 317
            .|::        ::.:.:|:|.|..:..:|..|.:.|:|.|.:|.:..|...|:|:||||:||:.
  Fly   260 LPSIQSNDKNLFLNLVTDLMRRGVFTLKNVEDESNIIVFGAFETTANAVYYTLMLLAMFPEYQER 324

  Fly   318 VFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGV 382
            .|||:..:||:.|:|:.|:||.:::|.||.:|:|:||:||.||::.||||..::||||..:|:||
  Fly   325 AFEEIKTIFPNTGDFDVSYADTQQMVYLDLILNESMRVIPPVPVVSRQTSQDLKLSNGIVVPKGV 389

  Fly   383 TLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLAL 447
            .:.|||:|.||:|.||||.|..||||:|||.|.:.:.||:|:||:||.:.|:||:.:|||||:.|
  Fly   390 QIAIDIYHMHRSKKIWGPDAETFNPDHFLPHNIQDKHPYAYIPFTKGIRNCIGWRYALISAKVTL 454

  Fly   448 AKILRNYMLSTTFLYKDLRFIDNTTMKLAEQPLLAVKRR 486
            ||:||||...|:|.:::|.|:::.||||...|||.:::|
  Fly   455 AKLLRNYRFKTSFPFENLYFVEDITMKLKSVPLLELQKR 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	165/432 (38%)
Cyp313a4	NP_650224.3	p450	33..465	CDD:299894	165/432 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450074
Domainoid	1	1.000	169	1.000	Domainoid score	I1170
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D28972at7147
OrthoFinder	1	1.000	-	-		FOG0008559
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900