DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp313a5 and Cyp4s3

DIOPT Version :9

Sequence 1:	NP_650168.1	Gene:	Cyp313a5 / 41486	FlyBaseID:	FBgn0038005	Length:	487	Species:	Drosophila melanogaster
Sequence 2:	NP_573003.2	Gene:	Cyp4s3 / 32444	FlyBaseID:	FBgn0030615	Length:	495	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	121/508 - (23%)
Similarity:	212/508 - (41%)	Gaps:	81/508 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IILCVYFLWSRRRFYIMML-----------KLPGPMGFPFIGLAFEYIRLKRKIRLRTILFKIYG 65
            :.|..:.||:....|:..:           .||||.    ||.....::....:.....|.:.:|
  Fly     4 LALVAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPT----IGELIANVKKGEILNWLKELREKHG 64

  Fly    66 KTVLTWIGLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERRKLLL 130
            .....|.|...:::..:|:.::.:..:.....:|...: .:...||.||||.....|:.|||||.
  Fly    65 PVFRIWFGKDLMVMFTDPEDIKQLLGNNQLLTKSRNYE-LLEPWLGKGLLTNGGESWHRRRKLLT 128

  Fly   131 PSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWSFKIAAQITMGDEVRNQANYQ 195
            |.|....:..|...:......||..|....:|...::.|.:..::.....:..||  ::..|..|
  Fly   129 PGFHFRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAMG--IKKHAQLQ 191

  Fly   196 NGNLLESYKALNNLIPIGVVMP------WLRNKYLGKLFSYEK--RRLEAA-----TQSNAFIKD 247
            :.:  |..:|:.::..   ||.      |.|   |...|.:.|  :..|||     .::|..|:
  Fly   192 SDS--EYVQAVQSICR---VMHKQSFSFWQR---LNVFFKHTKPGKEREAALKVLHDETNRVIR- 247

  Fly   248 IIDKKLSSTDNSSEP-------------ALIDRILNLVRIG--ELSYDDVMGEFSNIIFAASDTL 297
            :..::|....|..:|             |.:|.:|.....|  |||..|:..|....:|...||.
  Fly   248 LRREQLIQERNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDIREEVDTFMFEGHDTT 312

  Fly   298 SITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPLL 362
            |..:...|.|::..|..|...|||.:|:  .|.|       .|.:..|:.|:.||:|:.|:||..
  Fly   313 SSAIAFALSLLSKNPDVQQRAFEEASEL--EGRE-------KESMPYLEAVIKETLRIYPSVPFF 368

  Fly   363 IRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPFS 427
            .|:....:::.. ..:|:|.::...|:..||:...: |....|:||.|| .|::...|:::..||
  Fly   369 SRKVLEDLEVGK-LTVPKGASISCLIYMLHRDPKNF-PDPERFDPDRFL-VNEKQMHPFAFAAFS 430

  Fly   428 KGKKTCLGWKLSLISAKLALAKILRNYMLSTTFLYKDLRFI---DNTTMKLAE 477
            .|.:.|:|.|.:::..|.:||.:||:|           ||:   |:....|||
  Fly   431 AGPRNCIGQKFAMLELKTSLAMLLRSY-----------RFLPDKDHQPKPLAE 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	110/452 (24%)
Cyp4s3	NP_573003.2	p450	35..469	CDD:278495	114/472 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.860