Protein Alignment Cyp313a5 and Cyp3a2

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: XP_063127162.1
• Gene: Cyp3a2 / 266682
• RGDID: 708379
• Length: 505
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 129/523 - (24%)
• Similarity: 229/523 - (43%)
• Gaps: 75/523 - (14%)

  Fly     2 LTLQIFEAFAIIL-CVYFLWSRRRFYIMMLKLPGPMGFPFIGLAFEYIRLKRKIRLRTILFKIYG 65
            |||:.:...|:|| .:|.|.:.|........:|||...||:|....|  .|...|.....:|.||
  Rat     7 LTLETWVLLAVILVLLYRLGTHRHGIFKKQGIPGPKPLPFLGTVLNY--YKGLGRFDMECYKKYG 69

  Fly    66 KTVLTWIGLTPVLVTCEPKILED--------IFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHW 122
            |....:.|.|||....:.:::::        :||:........::.||:|        ..|:..|
  Rat    70 KIWGLFDGQTPVFAIMDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAVS--------VAKDEEW 126

  Fly   123 NERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVD-GGDINLLPELNKWSFKIAAQITMGD 186
            ...|.||.|:|.:..:....|::....:.||..|.:..: |..:.:......:|..:....:.|.
  Rat   127 KRYRALLSPTFTSGRLKEMFPIIEQYGDILVKYLKQEAETGKPVTMKKVFGAYSMDVITSTSFGV 191

  Fly   187 EVRNQANYQNGNLLESYKAL------NNLIPIGVVMPWLR-------------------NKYLGK 226
            .| :..|......:|..|.|      :.|....|:.|:|.                   .|::.:
  Rat   192 NV-DSLNNPKDPFVEKTKKLLRFDFFDPLFLSVVLFPFLTPIYEMLNICMFPKDSIAFFQKFVHR 255

  Fly   227 LFSYEKRRLEAATQSNA--FIKDIIDKKLSSTDNSSEPALIDRILNLVRIGELSYDDVMGEFSNI 289
            :   ::.||::..:.:.  |::.:::...:|.|..|..||.|             .:::.:....
  Rat   256 I---KETRLDSKHKVHRVDFLQLMLNAHNNSKDEVSHKALSD-------------VEIIAQSVIF 304

  Fly   290 IFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMR 354
            |||..:|.|.|::.||..:|..|..|..:.||:....||  :...::..:.::..||.||:||:|
  Rat   305 IFAGYETTSSTLSFVLYFLATHPDIQKKLQEEIDGALPS--KAPPTYDIVMEMEYLDMVLNETLR 367

  Fly   355 LIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARP 419
            |.|....|.|.....|:| :|.:||:|..:.|..:..|.:...| |:...|:|:.|..|||.:..
  Rat   368 LYPIGNRLERVCKKDIEL-DGLFIPKGSVVTIPTYALHHDPQHW-PKPEEFHPERFSKENKGSID 430

  Fly   420 PYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYMLSTTFLYKDLRFIDNTTMKLAEQPLLAVK 484
            ||.||||..|.:.|:|.:.:|::.||||.|:|:|:.....   |:.:.    .:||:.|.:|..:
  Rat   431 PYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPC---KETQI----PLKLSRQAILEPE 488

  Fly   485 RRI 487
            :.|
  Rat   489 KPI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	107/452 (24%)
Cyp3a2	XP_063127162.1	None