Protein Alignment Cyp313a5 and Cyp4a8

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_113793.2
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 105/490 - (21%)
• Similarity: 201/490 - (41%)
• Gaps: 67/490 - (13%)

  Fly     4 LQIFEAFAIILCVY----FLWSRRRFYIMMLKLPGPMGFPFIGLAFEYIRLKRKIRLRTILFKI- 63
            |||.....::|.::    |...||.......:.|.|....|.|     .::.:....:.||.::
  Rat    19 LQIATVLTVLLLLFKTAQFYLHRRWLLRATQQFPSPPSHWFFG-----HKIPKDQEFQDILTRVK 78

  Fly    64 -YGKTVLTWI-GLTPVLVTCEPKILEDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNNHWNERR 126
             :......|: |....:...:|..::.|....:..:..|.  :.::..:|.|||.|....|.:.|
  Rat    79 NFPSACPQWLWGSNVRIQVYDPDYMKLILGRSDPKSHHSY--RFLAPWIGYGLLLLNGQTWFQHR 141

  Fly   127 KLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKW--------SFKIAAQIT 183
            ::|.|:|..:.:..:|.::.:....:                  |:||        :.:|...||
  Rat   142 RMLTPAFHYDTLKPYVGIMADSVRIM------------------LDKWEQIVGQDSTLEIFQHIT 188

  Fly   184 MG--DEVRNQANYQNGN--LLESYKA-------LNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEA 237
            :.  |.:...|..|.|:  |...||:       ||||....:...:.:|..:..|.|..::...|
  Rat   189 LMTLDTIMKCAFSQEGSVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSNGRKARSA 253

  Fly   238 ATQSNAFIKDIIDKKLSSTDNSSEPALIDR--------ILNLVRI---GELSYDDVMGEFSNIIF 291
            ...::.....:|..:.:...:..|...:.:        ||...||   ..||..|:..|....:|
  Rat   254 WQLAHEHTDQVIKSRKAQLQDEEELQKVKQKRRLDFLDILLFARIENGSSLSDKDLRAEVDTFMF 318

  Fly   292 AASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLI 356
            ...||.:..::.:...:|..|::|....:|:..:...|...  :..||:|:......:.|.:|:.
  Rat   319 EGHDTTASGISWIFYALATNPEHQQGCRKEIQSLLGDGASI--TWDDLDKMPYTTMCIKEALRIY 381

  Fly   357 PAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPY 421
            |.|..:.|..|..:...:|..:|:|:|:|:..:..|.|..:| |....|:|..|.||:  :|..:
  Rat   382 PPVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLHHNPTVW-PNPEVFDPYRFAPES--SRHSH 443

  Fly   422 SYLPFSKGKKTCLGWKLSLISAKLALAKILRNYML 456
            |:||||.|.:.|:|.:.::...|:|:|..|..:.|
  Rat   444 SFLPFSGGARNCIGKQFAMNELKVAVALTLLRFEL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	92/423 (22%)
Cyp4a8	NP_113793.2	CYP4B-like	70..503	CDD:410771	94/434 (22%)