Protein Alignment Cyp313a5 and Cyp26b1

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_780684.1
• Gene: Cyp26b1 / 232174
• MGIID: 2176159
• Length: 512
• Species: Mus musculus
• Alignment Length: 496
• Identity: 129/496 - (26%)
• Similarity: 211/496 - (42%)
• Gaps: 74/496 - (14%)

  Fly    20 WSRRRFYIMMLKLP-GPMGFPFIGLAFEYI------RLKRKIRLRTILFK--IYGKTVLTWIGLT 75
            |:..|.....|.:| |.||||.||....::      :..|:.:...: ||  :.|:.::...|..
Mouse    37 WAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSGFQSSRREKYGNV-FKTHLLGRPLIRVTGAE 100

  Fly    76 PVLVTCEPKIL--EDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKNN----HWNERRKLLLPSFK 134
            .|     .|||  |....|......:.|:         ||..|:.|:    |.| :||:....|.
Mouse   101 NV-----RKILLGEHQLVSTEWPRSARVL---------LGPNTVANSIGDIHRN-KRKVFSKIFS 150

  Fly   135 NNAVLSFVPVLNNEANFLV---TLLAEFVDGGDINLLPELNKWSFKIAAQITMGDEVRNQANYQN 196
            :.|:.|::|.:.     ||   ||.|.......||:..|..:.:|::|.::.:|..:..:   ..
Mouse   151 HEALESYLPKIQ-----LVIQDTLRAWSSQPEAINVYQEAQRLTFRMAVRVLLGFSIPEE---DL 207

  Fly   197 GNLLESYKA-LNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSNAFIKDIIDKKLSSTDNSS 260
            |:|.|.|:. :.|:..:.|.:|          ||..:|.::|.......::..|.:||..|....
Mouse   208 GHLFEVYQQFVENVFSLPVDLP----------FSGYRRGIQARQILQKGLEKAIREKLQCTQGKD 262

  Fly   261 EPALIDRILNLVRI--GELSYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEEL- 322
            ....:|.::...:.  .|::..::......:||||..|.:....::::.:...|...:.:.|||
Mouse   263 YSDALDILIESSKEHGKEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELR 327

  Fly   323 AEVFPSGG----EFEASHADLEKLVKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVT 383
            |:....||    |.......|..|..||.|:.|.|||...|....|....:.:| :||.||:|.:
Mouse   328 AQGLLHGGGCPCEGTLRLDTLSSLRYLDCVIKEVMRLFTPVSGGYRTVLQTFEL-DGFQIPKGWS 391

  Fly   384 LMIDIFHTHRNKDIWGPQANAFNPDNF---LPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKL 445
            :|..|..||....:: ...|.|:||.|   ..|:|..|  :.||||..|.:||||..|    |||
Mouse   392 VMYSIRDTHDTAPVF-KDVNVFDPDRFSQARSEDKDGR--FHYLPFGGGVRTCLGKHL----AKL 449

  Fly   446 ALAKILRNYMLSTTFLYKDLRFIDNTTMKLAEQPL--LAVK 484
            .| |:|...:.||:......|.....|:.....|:  |:||
Mouse   450 FL-KVLAVELASTSRFELATRTFPRITLVPVLHPVDGLSVK 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	112/438 (26%)
Cyp26b1	NP_780684.1	CYP26B1	60..490	CDD:410730	119/473 (25%)