Protein Alignment Cyp313a5 and CYP4Z1

DIOPT Version :9

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_835235.1
• Gene: CYP4Z1 / 199974
• HGNCID: 20583
• Length: 505
• Species: Homo sapiens
• Alignment Length: 506
• Identity: 128/506 - (25%)
• Similarity: 210/506 - (41%)
• Gaps: 107/506 - (21%)

  Fly    12 IILC-------VYFLWSRRRFYIMMLKL-PGPMGFPFIGLAFEYIRLKRKIRLRTILFKIYGK-- 66
            |:||       |..|:.|||:.|..|.| |.|....|.|.. |:..:|.        |::|.|
Human    18 ILLCMSLLLFQVIRLYQRRRWMIRALHLFPAPPAHWFYGHK-EFYPVKE--------FEVYHKLM 73

  Fly    67 -----TVLTWIG-LTPVLVTCEP---KIL---EDIFTSPNCSNRSSVVDKAISSCLGLGLLTLKN 119
                 .|..|:| .|......:|   |||   :|        .:|:|..|.:.|.:|.||:||..
Human    74 EKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQD--------PKSAVSHKILESWVGRGLVTLDG 130

  Fly   120 NHWNERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINLLPELNKWS--------- 175
            :.|.:.|:::.|.|..:.:..|:.:::.....:                  ||||.
Human   131 SKWKKHRQIVKPGFNISILKIFITMMSESVRMM------------------LNKWEEHIAQNSRL 177

  Fly   176 --FKIAAQITMGDEVR----NQANYQNGNLLESY-KALNNLIPIGVVMPWLRNKYL--------- 224
              |:..:.:|:...::    :|.:.|..:.|:|| ||:.||..|.   ....|.:|
Human   178 ELFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKIS---NQRMNNFLHHNDLVFKF 239

  Fly   225 ---GKLFSYEKRRLEAATQSNAFIKDIIDKKLSSTDNSSEPALIDRILNLVRI---------GEL 277
               |::||...:.|...|:     |.|.|:|.|..|...:.....|..:.:.|         .:.
Human   240 SSQGQIFSKFNQELHQFTE-----KVIQDRKESLKDKLKQDTTQKRRWDFLDILLSAKSENTKDF 299

  Fly   278 SYDDVMGEFSNIIFAASDTLSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKL 342
            |..|:..|....:||..||.|..::.:|..:|.:|::|....:|:.|:...|......|  |.::
Human   300 SEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEH--LSQM 362

  Fly   343 VKLDRVLHETMRLIPAVPLLIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIW-GPQANAFN 406
            ......:.|.:||...|..:.|.....|...:|..:|.|:|:.|:|:..|.|...| .||  .||
Human   363 PYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQ--VFN 425

  Fly   407 PDNFLPENKRARPPYSYLPFSKGKKTCLGWKLSLISAKLALAKILRNYMLS 457
            |..|..||.....||:::|||.|.:.|:|...::|..|:|:|..|..:.|:
Human   426 PLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLA 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	p450	33..458	CDD:299894	117/477 (25%)
CYP4Z1	NP_835235.1	p450	47..500	CDD:278495	117/477 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D825914at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920