Protein Alignment Cyp313a5 and Cyp4a12b

DIOPT Version :10

• Sequence 1: NP_650168.1
• Gene: Cyp313a5 / 41486
• FlyBaseID: FBgn0038005
• Length: 487
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 485
• Identity: 101/485 - (20%)
• Similarity: 200/485 - (41%)
• Gaps: 85/485 - (17%)

  Fly    40 FIGLAFEYIRLKRKIRLRTILFK-----IYGKTVLT-----------WIGLTPVLVTCEPKILED 88
            |.|...||:::...:.|..:|||     ::.:.:|:           |:....:|   :.:.|:|
Mouse    11 FPGSISEYLQVASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGHKIL---KDQDLQD 72

  Fly    89 IFTS----PN-CSN-------RSSVVD-------------------KAISSCLGLGLLTLKNNHW 122
            |.|.    |: |..       |..|.|                   :.::..:|.|||.|....|
Mouse    73 ILTRIKNFPSACPQWLWGSKVRIQVYDPDYMKLILGRSDPKAHGSYRFLAPWIGRGLLLLDGQTW 137

  Fly   123 NERRKLLLPSFKNNAVLSFVPVLNNEANFLVTLLAEFVDGGDINL----------LPELNKWSFK 177
            .:.|::|.|:|..:.:..:..::.:..:.::....:.| |.|..|          |..:.|.:|.
Mouse   138 FQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQIV-GQDSTLEIFQHITLMTLDTIMKCAFS 201

  Fly   178 IAAQITMGDEVRNQANYQNGNLLESYKALNNLIPIGVVMPWLRNKYLGKLFSYEKRRLEAATQSN 242
            ....:.:.   |...:|     :::.:.||||..:.|...:.:|..:.::.|.......|...::
Mouse   202 HEGSVQLD---RKYKSY-----IQAVEDLNNLFFLRVRNIFHQNDIIYRVSSNGCLANSACQLAH 258

  Fly   243 AFIKDIIDKKLSSTDNSSEPALIDR--------ILNLVRI---GELSYDDVMGEFSNIIFAASDT 296
            .....:|..:.|...:..|...:.:        ||...|:   ..||..|:..|....:|...||
Mouse   259 DHTDQVIKSRRSQLQDEEELEKLKKKRRLDFLDILLFARMENGKSLSDKDLRAEVDTFMFEGHDT 323

  Fly   297 LSITVNNVLILMAMFPKYQDNVFEELAEVFPSGGEFEASHADLEKLVKLDRVLHETMRLIPAVPL 361
            .:..::.:...:|..|::|....:|:..:...|...  :..||:|:......:.|.:|:.|.||.
Mouse   324 TASGISWIFYALATNPEHQQRCRKEIQSLLGDGASI--TWNDLDKMPYTTMCIKEALRIYPPVPS 386

  Fly   362 LIRQTSHSIQLSNGFYIPEGVTLMIDIFHTHRNKDIWGPQANAFNPDNFLPENKRARPPYSYLPF 426
            :.|:.|..:...:|..:|:|:.:|:..:..|.|..:| |....|:|..|.|.:  :|..:|:|||
Mouse   387 VSRELSSPVTFPDGRSLPKGIHVMLSFYGLHHNPTVW-PNPEVFDPSRFAPGS--SRHSHSFLPF 448

  Fly   427 SKGKKTCLGWKLSLISAKLALAKILRNYML 456
            |.|.:.|:|.:.::...|:|:|..|..:.|
Mouse   449 SGGARNCIGKQFAMNELKVAVALTLLRFEL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp313a5	NP_650168.1	CYP313-like	65..482	CDD:410680	93/455 (20%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	90/423 (21%)